Tag: inhibitor

For research use only. We do not sell to patients. GK563 CAS No. : 2351820-19-2 Biological Activity：GK563 is a selective Ca2+-independent phospholipase A2 (GVIA iPLA2) inhibitor with an IC50 value of 1 nM. GK563 is 22000 times more active against GVIA iPLA2 than GIVA cPLA2. GK563 reduces β-cell apoptosis induced by proinflammatory cytokines, raising the […]

For research use only. We do not sell to patients. ZIKV-IN-4 Biological Activity：ZIKV-IN-4 (compound 5b) is a low-cytotoxicity and acid-stable anti-ZIKV agent (EC50=3.49 μM). ZIKV-IN-4 effectively inhibits the activity of ZIKV NS5 MTase. Research Area：Infection Targets：Virus Protease Related Small Molecules:SRPIN340;Aminothiazole;CYP2C9/CYP2C19-IN-1;L-Lysine;L-Lysine-13C6,15N2,d9 dihydrochloride;4E2RCat;ESI-09;Tubacin;Lycorine;PCL 016;NGI-1;(-)-α-Pinene;Encephalitic alphavirus-IN-1;HCVcc-IN-1;L-Lysine-d4 hydrochloride;ZINC03129319;SARS-CoV-2 Mpro-IN-4;Palmatine;Ensitrelvir;NS2B/NS3-IN-6;NS2B/NS3-IN-4;L-Lysine-d9 hydrochloride;Hinokitiol;L-Lysine-15N-1 dihydrochloride Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  […]

For research use only. We do not sell to patients. Stauprimide CAS No. : 154589-96-5 Biological Activity：Stauprimide is a staurosporine analog that promotes embryonic stem cell (ESC) differentiation. Stauprimide is a non-broad spectrum inhibitor that binds to the MYC transcription factor NME2 and blocks its nuclear localization in ESCs, which results in down-regulation of MYC […]

For research use only. We do not sell to patients. Benidipine hydrochloride CAS No. : 91599-74-5 Biological Activity：Benidipine hydrochloride is a dihydropyridine calcium channel blocker for the treatment of high blood pressure (hypertension). Research Area：Cardiovascular Disease Targets：Calcium Channel Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Membrane Transporter/Ion […]

For research use only. We do not sell to patients. COX-2/5-LOX-IN-3 CAS No. : 2481484-51-7 Biological Activity：COX-2/5-LOX-IN-3 (compound 5b) is a potent and dual COX-2/5-LOX inhibitor with IC50 values of 45.73, 5.45 and 4.33 μM for COX-1, COX-2, and 5-LOX, respectively. COX-2/5-LOX-IN-3 has the potential for the research of inflammation diseases. Research Area：Inflammation/Immunology Targets：Lipoxygenase|COX Related […]

For research use only. We do not sell to patients. JNK3 inhibitor-2 CAS No. : 2366264-18-6 Biological Activity：JNK3 inhibitor-2 is a potent and selective JNK3 inhibitor with IC50 values of >100, >100, 0.25 µM for JNK1, JNK2, JNK3, respectively. JNK3 inhibitor-2 shows DDR1 and EGFR (T790M, L858R) inhibition. Research Area：Cancer|Inflammation/Immunology Targets：Discoidin Domain Receptor|JNK Related Small […]

For research use only. We do not sell to patients. RVX-297 CAS No. : 1044871-04-6 Biological Activity：RVX-297 is a potent, orally active BET bromodomain inhibitor with selectivity for BD2. RVX-297 shows IC50s of 0.08, 0.05, and 0.02 μM for BRD2(BD2), BRD3(BD2), and BRD4(BD2), respectively. RVX-297 suppresses inflammatory gene expression in multiple immune cell types. RVX-297 […]

For research use only. We do not sell to patients. Shionone CAS No. : 10376-48-4 Biological Activity：Shionone is the major triterpenoid isolated from Aster tataricus, has anti-tussive, anti-inflammatory activities[2]. Shionone possesses a unique six-membered tetracyclic skeleton and 3-oxo-4-monomethyl structure. Research Area：Inflammation/Immunology Targets：Others Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Natural Product Library;Medicine […]

For research use only. We do not sell to patients. Oritavancin CAS No. : 171099-57-3 Biological Activity：Oritavancin (LY 333328) is an orally active glycopeptide antibiotic with activity against gram-positive organisms. Oritavancin shows antibacterial effect against multidrug-resistant S. pneumoniae. Oritavancin inhibits cell wall synthesis and disrupts the membrane potential[2]. Research Area：Infection|Inflammation/Immunology Targets：Bacterial|Antibiotic Related Small Molecules:Sandramycin;LLO (91-99);Gepotidacin;Monascorubrin;Azlocillin […]

For research use only. We do not sell to patients. Avutometinib CAS No. : 946128-88-7 Biological Activity：Avutometinib (Ro 5126766) is a first-in-class dual MEK/RAF inhibitor that allosterically inhibits BRAFV600E, CRAF, MEK, and BRAF (IC50: 8.2, 56, 160 nM, and 190 nM, respectively). Research Area：Cancer Targets：MEK|Raf Related Screening Libraries:Clinical Compound Library Plus;Bioactive Compound Library Plus;Immunology/Inflammation Compound […]