Tag: Agonist|Inhibitor

For research use only. We do not sell to patients. Pyrantel CAS No. : 15686-83-6 Biological Activity：Pyrantel is an orally active anthelmintic and an agonist of the nicotinic acetylcholine receptor (nAChR). Pyrantel can cause spasmodic muscle paralysis in parasites. Pyrantel can be used in the study of parasitic infections such as ascariasis, hookworm infections, intestinal […]

For research use only. We do not sell to patients. Pyrantel tartrate CAS No. : 33401-94-4 Biological Activity：Pyrantel tartrate is an orally active anthelmintic and an agonist of the nicotinic acetylcholine receptor (nAChR). Pyrantel tartrate can cause spasmodic muscle paralysis in parasites. Pyrantel tartrate can be used in the study of parasitic infections such as […]

For research use only. We do not sell to patients. Zidovudine-d3 Biological Activity：Zidovudine-d3 (Azidothymidine-d3) is the deuterium labeled Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection. Zidovudine increases CRISPR/Cas9-mediated editing frequency. Research Area：Infection Targets：CRISPR/Cas9|HIV Related Small Molecules:HIV-1 TAT (48-60);Seletracetam lithium;HIV-IN-2;Triptonine B;FC131;Peritassine A;Flavopiridol;TAT (48-57);FGI-106 tetrahydrochloride;(Z)-9-Propenyladenine;Apabetalone;Decanoyl-RVKR-CMK TFA;ONX-0914 TFA;Apelin-36(rat, mouse);Ulonivirine;Islatravir;HIV-1 inhibitor-19 […]

For research use only. We do not sell to patients. Gardiquimod CAS No. : 1020412-43-4 Biological Activity：Gardiquimod, an imidazoquinoline analog, is a TLR7/8 agonist. Gardiquimod could inhibit HIV-1 infection of macrophages and activated peripheral blood mononuclear cells (PBMCs). Gardiquimod specifically activates TLR7 when used at concentrations below 10 μM[2]. Research Area：Cancer|Infection Targets：HIV|Toll-like Receptor (TLR) Related Small […]

For research use only. We do not sell to patients. Amitraz CAS No. : 33089-61-1 Biological Activity：Amitraz is a non-systemic acaricide and insecticide, with alpha-adrenergic agonist activity, interaction with octopamine receptors of the central nervous system and inhibition of monoamine oxidases and prostaglandin synthesis. Research Area：Infection|Endocrinology Targets：Parasite|Adrenergic Receptor|Monoamine Oxidase Related Screening Libraries:Bioactive Compound Library Plus;Anti-Infection […]

For research use only. We do not sell to patients. α7 nAchR-JAK2-STAT3 agonist 1 CAS No. : 2108714-20-9 Biological Activity：α7 nAchR-JAK2-STAT3 agonist 1 is a potent α7 nAchR-JAK2-STAT3 agonist, with an IC50 value of 0.32 μM for nitric oxide (NO). α7 nAchR-JAK2-STAT3 agonist 1 effectively suppresses the expression of iNOS, IL-1β, and IL-6 in murine […]

For research use only. We do not sell to patients. Mal-VC-PAB-(N-Me-amide-C3)-ADU-S100 triethylamine CAS No. : 2249935-19-9 Biological Activity：Mal-VC-PAB-(N-Me-amide-C3)-ADU-S100 triethylamine is an immune stimulator antibody conjugate (ISAC) comprising an anti-human epidermal growth factor receptor 2 (HER2) antibody, a STING agonist (ADU-S100) and a linker. Mal-VC-PAB-(N-Me-amide-C3)-ADU-S100 triethylamine can be uesd for cancer research (WO2018200812A1; example 5). Research […]

For research use only. We do not sell to patients. DSP-1053 CAS No. : 1176326-76-3 Biological Activity：DSP-1053, a benzylpiperidine derivative, is a potent Serotonin Transporter (SERT) inhibitor with a Ki of 1.02 nM. DSP-1053 shows partial 5-HT1A receptor agonistic activity with a Ki of 5.05 nM. DSP-1053 has antidepressant activity. Research Area：Neurological Disease Targets：5-HT Receptor|Serotonin Transporter Related […]

For research use only. We do not sell to patients. Naphazoline CAS No. : 835-31-4 Biological Activity：Naphazoline (Naphthazoline) is a potent α-adrenergic receptor agonist. Naphazoline reduces vascular hyperpermeability and promotes vasoconstriction. Naphazoline reduces the levels of inflammatory factors (TNF-α, IL-1β and IL-6), cytokines (IFN-γ and IL-4), IgE, GMCSF, and NGF。Naphazoline can be used for non-bacterial […]

For research use only. We do not sell to patients. Oxantel CAS No. : 36531-26-7 Biological Activity：Oxantel (CP-14445), a m-oxyphenol derivative of Pyrantel (HY-12641), is a N-subtype AChR agonist. Oxantel is an anthelmintic, with excellent trichuricidal properties[2]. Research Area：Infection Targets：Parasite|nAChR Related Small Molecules:(+)-Isopulegol;SR9186;Antileishmanial agent-2;Azlocillin sodium salt;Spinosad;SQ109;Trypanothione synthetase-IN-3;Pyrantel;α-Terpinene;Dehydrocorydaline;Niclosamide monohydrate;Febrifugine dihydrochloride;Antimalarial agent 15;Cycloguanil hydrochloride;Anti-infective agent 6;Morantel tartrate;Sulfiram;NS […]