Antagonist|Inhibitor

For research use only. We do not sell to patients. 6-Mercaptopurine-13C2,15N CAS No. : 1190008-04-8 Biological Activity：6-Mercaptopurine-13C2,15N (Mercaptopurine-13C2,15N) is the 13C- and 15N-labeled 6-Mercaptopurine. 6-Mercaptopurine is a purine analogue which acts as an antagonist of the endogenous purines and has been widely used as antileukemic agent and immunosuppressive drug. Research Area：Cancer Targets：Nucleoside Antimetabolite/Analog|Autophagy|Endogenous Metabolite Related […]

For research use only. We do not sell to patients. FC131 CAS No. : 606968-52-9 Biological Activity：FC131 is a potent CXCR4 antagonist. FC131 inhibits [125I]-SDF-1 binding to CXCR4 with an IC50 of 4.5 nM. FC131 has anti-HIV activity. Research Area：Infection Targets：CXCR|HIV Related Small Molecules:Nicotinamide N-oxide;HIV-1 TAT (48-60);Seletracetam lithium;HIV-IN-2;Triptonine B;Peritassine A;CXCR4 antagonist 2;Flavopiridol;AMG 487 (S-enantiomer);TAT (48-57);FGI-106 […]

For research use only. We do not sell to patients. Glaucine CAS No. : 475-81-0 Biological Activity：Glaucine (O,O-Dimethylisoboldine) is an alkaloid isolated from Glaucium flavum with antitussive, bronchodilation and anti-inflammatory properties. Glaucine is a selective and orally active phosphodiesterase 4 (PDE4) inhibitor with Kis of 3.4 µM in human bronchus and polymorphonuclear leukocytes. Glaucine is […]

For research use only. We do not sell to patients. Picrotoxinin CAS No. : 17617-45-7 Biological Activity：Picrotoxinin, a potent convulsant, is a chloride channel blocker. Picrotoxinin is a noncompetitive GABAA receptor antagonist, which negatively modulates the action of GABA on GABAA receptors. Picrotoxinin inhibits α1β2γ2L GABAA receptor with an IC50 of 1.15 μM. Research Area：Neurological […]

For research use only. We do not sell to patients. Ritanserin CAS No. : 87051-43-2 Biological Activity：Ritanserin (R 55667) is a highly potent, relatively selective, orally active, long acting antagonist of 5-HT2 receptor, with an IC50 of 0.9 nM, less active on Histamine H1, Dopamine D2, Adrenergic α1, Adrenergic α2 receptors. Research Area：Neurological Disease Targets：Dopamine […]

For research use only. We do not sell to patients. Metoprolol succinate CAS No. : 98418-47-4 Biological Activity：Metoprolol succinate is an orally active, selective β1-adrenoceptor antagonist. Metoprolol succinate shows anti-inflammation, antitumor and anti-angiogenic properties[2][3]. Research Area：Cardiovascular Disease|Endocrinology|Cancer Targets：Adrenergic Receptor|Apoptosis Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Apoptosis […]

For research use only. We do not sell to patients. KRH-3955 hydrochloride CAS No. : 2253744-59-9 Biological Activity：KRH-3955 hydrochloride is an orally bioavailable CXCR4 antagonist. KRH-3955 hydrochloride inhibits SDF-1α binding to CXCR4 with an IC50 of 0.61 nM. KRH-3955 hydrochloride is also a highly potent and selective inhibitor of X4 HIV-1, with an EC50 of […]

For research use only. We do not sell to patients. Brompheniramine maleate CAS No. : 980-71-2 Biological Activity：Brompheniramine ((±)-Brompheniramine) maleate is a potent and orally active antihistamine of the alkylamine class. Brompheniramine maleate is a selective histamine H1 receptor antagonist with a Kd of 6.06 nM. Brompheniramine maleate can block the hERG channels, calcium channels, […]