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CAS No. : 475-81-0

Biological Activity:Glaucine (O,O-Dimethylisoboldine) is an alkaloid isolated from Glaucium flavum with antitussive, bronchodilation and anti-inflammatory properties. Glaucine is a selective and orally active phosphodiesterase 4 (PDE4) inhibitor with Kis of 3.4 µM in human bronchus and polymorphonuclear leukocytes. Glaucine is also a non-selective α-adrenoceptor antagonist, a Ca2+ entry blocker, and a weak dopamine D1 and D2 receptor antagonist. Glaucine has antioxidative and antiviral activities[2][3].

Research Area:Infection|Inflammation/Immunology

Targets:Phosphodiesterase (PDE)|Dopamine Receptor|Adrenergic Receptor|Influenza Virus|Calcium Channel

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