Activator|Antagonist

For research use only. We do not sell to patients. Capsazepine CAS No. : 138977-28-3 Biological Activity：Capsazepine is a synthetic analogue of the sensory neurone excitotoxin, and an antagonist of TRPV1 receptor with an IC50 of 562 nM. Research Area：Cancer Targets：TRP Channel|Apoptosis Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;Membrane Transporter/Ion Channel Compound Library;Neuronal Signaling […]

For research use only. We do not sell to patients. GYKI-47261 dihydrochloride CAS No. : 1217049-32-5 Biological Activity：GYKI-47261 dihydrochloride is a competitive, orally active, and selective AMPA receptor antagonist with an IC50 of 2.5 μM. GYKI-47261 has broad spectrum anticonvulsive activity and neuroprotective effects. GYKI-47261 dihydrochloride is also a potent inducer of CYP2E1[2]. Research Area：Neurological […]

For research use only. We do not sell to patients. CRTh2 antagonist 3 CAS No. : 312928-72-6 Biological Activity：CRTh2 antagonist 3 is a potent chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTh2) antagonist. CRTh2 antagonist 3 enhances the activity of PDK1 toward a short peptide substrate, with an EC50 of 2 μM and a Kd […]

For research use only. We do not sell to patients. UNC1215 CAS No. : 1415800-43-9 Biological Activity：UNC1215 is a potent and selective inhibitor for the methyllysine (Kme) reading domain function of L3MBTL3 with a Kd value of 120 nM and an IC50 of 40 nM. UNC1215 has the potential to treat malignant brain tumor. Research […]

For research use only. We do not sell to patients. TP508 CAS No. : 121341-81-9 Biological Activity：TP508 is a 23-amino acid nonproteolytic thrombin peptide that represents a portion of the receptor-binding domain of thrombin molecule. TP508 activates endothelial NO synthase (eNOS) and stimulates production of NO in human endothelial cells. TP508 activates endothelial cells and […]

For research use only. We do not sell to patients. LE135 CAS No. : 155877-83-1 Biological Activity：LE135 is a potent RAR antagonist that binds selectively to RARα (Ki of 1.4 μM) and RARβ (Ki of 220 nM), and has a higher affinity to RARβ. LE135 is highly selective over RARγ, RXRα, RXRβ and RXRγ. LE135 […]

For research use only. We do not sell to patients. Celiprolol hydrochloride CAS No. : 57470-78-7 Biological Activity：Celiprolol (REV 5320) is a potent, cardioselective and orally active β1-andrenoceptor r antagonist with partial β2 agonist activity, with Ki values of 0.14-8.3 μM. Celiprolol has antihypertensive and antianginal activity, and can be used for the research of […]

For research use only. We do not sell to patients. Antagonist G CAS No. : 115150-59-9 Biological Activity：Antagonist G is a potent vasopressin antagonist. Antagonist G is also a weak antagonist of GRP and Bradykinin. Antagonist G induces AP-1 transcription and sensitizes cells to chemotherapy[2]. Research Area：Cancer Targets：Apoptosis|Vasopressin Receptor Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis […]