Tag: Inducer|Antagonist

For research use only. We do not sell to patients. Xevinapant CAS No. : 1071992-99-8 Biological Activity：Xevinapant (AT-406) is a potent and orally bioavailable Smac mimetic and an antagonist of IAPs, and it binds to XIAP, cIAP1, and cIAP2 proteins with Ki of 66.4, 1.9, and 5.1 nM, respectively. Research Area：Cancer Targets：IAP|Apoptosis Related Screening Libraries:Drug […]

For research use only. We do not sell to patients. SCH79797 dihydrochloride CAS No. : 1216720-69-2 Biological Activity：SCH79797 dihydrochloride is a highly potent, selective nonpeptide protease activated receptor 1 (PAR1) antagonist. SCH79797 dihydrochloride inhibits binding of a high-affinity thrombin receptor-activating peptide to PAR1 with an IC50 of 70 nM and a Ki of 35 nM. […]

For research use only. We do not sell to patients. Irbesartan hydrochloride CAS No. : 329055-23-4 Biological Activity：Irbesartan (SR-47436) hydrochloride is an orally active Ang II type 1 (AT1) receptor blocker (ARB). Irbesartan hydrochloride can relax the blood vessels, low blood pressure and increase the supply of blood and oxygen to the heart. Irbesartan hydrochloride […]

For research use only. We do not sell to patients. Telmisartan-13C,d3 CAS No. : 1261396-33-1 Biological Activity：Telmisartan-13C,d3 is the 13C- and deuterium labeled Telmisartan. Telmisartan is a potent, long lasting antagonist of angiotensin II type 1 receptor (AT1), selectively inhibiting the binding of 125I-AngII to AT1 receptors with IC50 of 9.2 nM. Research Area：Cardiovascular Disease|Endocrinology […]

For research use only. We do not sell to patients. Sertindole CAS No. : 106516-24-9 Biological Activity：Sertindole (Lu 23-174) is an orally active 5-HT2A, 5-HT2C, dopamine D2, and αl-adrenergic receptors antagonist. Sertindole shows antipsychotic activity and anti-proliferative activity to multiple cancer cells[2][3]. Research Area：Neurological Disease|Cancer Targets：Dopamine Receptor|Adrenergic Receptor|5-HT Receptor|Autophagy Related Screening Libraries:Drug Repurposing Compound Library […]

For research use only. We do not sell to patients. SM-164 CAS No. : 957135-43-2 Biological Activity：SM-164 is a cell-permeable Smac mimetic compound. SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains with an IC50 value of 1.39 nM and functions as an extremely potent antagonist of XIAP. Research Area：Cancer Targets：IAP|Apoptosis Related […]

For research use only. We do not sell to patients. Chloropyramine CAS No. : 59-32-5 Biological Activity：Chloropyramine is competitive reversible H1 receptor antagonist. Chloropyramine also has anti-tumour activity in breast cancer. Chloropyramine can be used for the research of allergic conditions, such as conjunctivitis and bronchial asthma[2]. Research Area：Cancer|Cardiovascular Disease Targets：Histamine Receptor|Apoptosis Related Small Molecules:Physalin […]

For research use only. We do not sell to patients. W146 CAS No. : 909725-61-7 Biological Activity：W146 is a selective antagonist of sphingosine-1-phosphate receptor 1 (S1PR1) with an EC50 value of 398 nM. Research Area：Cancer|Metabolic Disease Targets：LPL Receptor|Apoptosis Related Small Molecules:Physalin A;Bomedemstat ditosylate;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;Xevinapant;GSK2018682;Mangiferin;Cambinol;Antioxidant agent-5;Apoptosis inducer 9;Bafetinib;Cyclovirobuxine D;STAT3-IN-10 Trending products：Recombinant Proteins  […]

For research use only. We do not sell to patients. Fimasartan CAS No. : 247257-48-3 Biological Activity：Fimasartan(BR-A-657) is a non-peptide angiotensin II receptor antagonist used for the treatment of hypertension and heart failure. IC50 value: Target: AT1 receptor antagonist in vitro: Fimasartan suppressed the expressions of inducible nitric oxide synthase (iNOS) by down-regulating its transcription, […]

For research use only. We do not sell to patients. Ozarelix CAS No. : 295350-45-7 Biological Activity：Ozarelix (D-63153) is a GnRH antagonist. Ozarelix induces cell apoptosis and arrests cell in G2/M phase. Ozarelix can be used in the research of prostate cancer. Research Area：Cancer Targets：GnRH Receptor|Apoptosis Related Small Molecules:Physalin A;Bomedemstat ditosylate;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor […]