Sulindac

For research use only. We do not sell to patients. Sulindac CAS No. : 38194-50-2 Biological Activity:Sulindac (MK-231) is an orally active nonsteroidal anti-inflammatory agent. Sulindac also is an immunomodulatory agent. Sulindac can be used for the research of arthritis of the spine, gouty arthritis and kinds of cancer including colorectal cancer (CRC) and lung […]

JNJ-40418677

For research use only. We do not sell to patients. JNJ-40418677 CAS No. : 1146594-87-7 Biological Activity:JNJ-40418677 is an orally active modulator of γ-secretase, can cross the blood-brain barrier. JNJ-40418677 inhibits Aβ42 and NS2B-NS3 protease, with IC50s of 200 nM and 3.9 μM, respectively. JNJ-40418677 displays good biological tolerance, can be use for Alzheimer’s disease […]

(-)-α-Pinene

For research use only. We do not sell to patients. (-)-α-Pinene CAS No. : 7785-26-4 Biological Activity:(-)-α-Pinene is a monoterpene and shows sleep enhancing property through a direct binding to GABAA-benzodiazepine (BZD) receptors by acting as a partial modulator at the BZD binding site. Research Area:Neurological Disease Targets:Bacterial|GABA Receptor|Endogenous Metabolite|Virus Protease Related Screening Libraries:Natural Product […]

Cavosonstat

For research use only. We do not sell to patients. Cavosonstat CAS No. : 1371587-51-7 Biological Activity:Cavosonstat (N91115) is an orally active S-nitrosoglutathione reductase (GSNOR) inhibitor. Cavosonstat is a CFTR stabilizer, and can be used for cystic fibrosis research. Research Area:Inflammation/Immunology Targets:CFTR|GSNOR Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Immunology/Inflammation […]

Gamma-glutamylcysteine TFA

For research use only. We do not sell to patients. Gamma-glutamylcysteine TFA CAS No. : 283159-88-6 Biological Activity:Gamma-glutamylcysteine (γ-Glutamylcysteine) TFA, an intermediate in glutathione (GSH) synthesis, is a dipeptide served as an essential cofactor for the antioxidant enzyme glutathione peroxidase (GPx). Gamma-glutamylcysteine TFA also upregulates the level of the anti-inflammatory cytokine IL-10 and reduces the […]

Davunetide

For research use only. We do not sell to patients. Davunetide CAS No. : 211439-12-2 Biological Activity:Davunetide is an eight amino acid snippet derived from activity-dependent neuroprotective protein (ADNP), a neurotrophic factor that exists in the mammalian CNS. Davunetide possesses neuroprotective, neurotrophic and cognitive protective roperties. Davunetide, a microtubule-stabilizing peptide, interacts with and stabilises neuron-specific […]

Avanafil

For research use only. We do not sell to patients. Avanafil CAS No. : 330784-47-9 Biological Activity:Avanafil (TA-1790) is a potent and selective phosphodiesterase-5 (PDE-5) inhibitor with IC50 values of 5.2 nM, 630 nM, 5700 nM, 6200 nM, 12000 nM, 27000 nM, 51000 nM and 53000 nM for PDE-5, PDE-6, PDE-4, PDE-10, PDE-8, PDE-7, PDE-2 […]

Sodium thiocyanate

For research use only. We do not sell to patients. Sodium thiocyanate CAS No. : 540-72-7 Biological Activity:Sodium thiocyanate reduces plasma levels of the pro-inflammatory cytokine IL-6, and increases the anti-inflammatory cytokine IL-10 levels. Sodium thiocyanate also significantly reduces of ROS formation. Research Area:Inflammation/Immunology Targets:Interleukin Related|Reactive Oxygen Species Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library […]

Chlorotrianisene

For research use only. We do not sell to patients. Chlorotrianisene CAS No. : 569-57-3 Biological Activity:Chlorotrianisene is a long-acting non-steroidal estrogen and an orally active estrogen receptor modulator. Chlorotrianisene exhibits antiestrogenic activity. Chlorotrianisene potently inhibits the enzyme COX-1 and inhibits platelet aggregation in whole blood[2][3]. Research Area:Endocrinology|Cardiovascular Disease Targets:Estrogen Receptor/ERR|COX Related Screening Libraries:Natural Product-like […]

Y-27632

For research use only. We do not sell to patients. Y-27632 CAS No. : 146986-50-7 Biological Activity:Y-27632 is an orally active, ATP-competitive inhibitor of ROCK-I and ROCK-II, with Kis of 220 and 300 nM, respectively. Y-27632 attenuates Doxorubicin-induced apoptosis of human cardiac stem cells. Y-27632 also suppresses dissociation-induced apoptosis of murine prostate stem/progenitor cells. Y-27632 […]