For research use only. We do not sell to patients.
JNJ-40418677
CAS No. : 1146594-87-7
Biological Activity：JNJ-40418677 is an orally active modulator of γ-secretase, can cross the blood-brain barrier. JNJ-40418677 inhibits Aβ42 and NS2B-NS3 protease, with IC50s of 200 nM and 3.9 μM, respectively. JNJ-40418677 displays good biological tolerance, can be use for Alzheimer’s disease research[2][3].
Research Area：Neurological Disease
Targets：γ-secretase|Amyloid-β
Related Small Molecules:β-Amyloid (13-27);γ-Secretase modulator 4;ELN318463;Saikosaponin C;β-Amyloid (1-42), (rat/mouse) (TFA);β-Amyloid (12-28) (TFA);BuChE-IN-5;Ginsenoside Rg1;MDR-1339;Crenigacestat;Aβ42-IN-1 free base;β-Amyloid (11-22);Fosciclopirox;20(S)-Ginsenoside Rg3;β-Amyloid (31-35);Aβ-IN-1;Qingyangshengenin B;gamma-secretase modulator 3;HDAC6-IN-6;β-Amyloid (1-37) (human);CGP52411;Astrophloxine;γ-Secretase modulator 11 hydrochloride;γ-Secretase modulator 12;Aβ42-IN-2;δ-Secretase inhibitor 11
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
About Us:
- MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use；
- Structurally and synthetically diverse biologically active compounds；
- roduct quality is the key to our success and we take pride in offering only the highest-grade products.；
- We provide HNMR, LC-MS, HPLC, stability testing and activity assays of our products to clients.；
- Product identity, quality, purity and activity are assured by our robust quality control programs and procedures.；
- Customized order volume ranging from milligrams to kilograms scale；
Structurally and synthetically diverse biologically active compounds；
We provide customer-oriented services. To explore more, please contact us at [email protected]. Our team will gladly assist you.
