Inhibitor|Modulator

For research use only. We do not sell to patients. Atazanavir CAS No. : 198904-31-3 Biological Activity：Atazanavir (BMS-232632), a highly selective HIV-1 protease inhibitor, is the first protease inhibitor approved for once-daily administration. Atazanavir (BMS-232632) is a substrate and inhibitor of CYP3A4, and an inhibitor and inducer of P-glycoprotein (P-gp)[2]. Atazanavir is also a SARS-CoV […]

For research use only. We do not sell to patients. L-Theanine CAS No. : 3081-61-6 Biological Activity：L-Theanine (L-Glutamic Acid γ-ethyl amide) is a non-protein amino acid contained in green tea leaves, which blocks the binding of L-glutamic acid to glutamate receptors in the brain, and with neuroprotective, anticancer and anti-oxidative activities. L-Theanine can pass through […]

For research use only. We do not sell to patients. Phenyltoloxamine CAS No. : 92-12-6 Biological Activity：Phenyltoloxamine (Bistrimin) is an antihistamine agent with sedative and analgesic effects. Phenyltoloxamine also has potent Sigma-1 receptor binding affinity (Ki: 160 nM)[2][3]. Research Area：Inflammation/Immunology|Neurological Disease Targets：Sigma Receptor|Histamine Receptor|Cytochrome P450 Related Small Molecules:SR9186;AMG-208;CYP1B1-IN-1;CYP2C9/CYP2C19-IN-1;Tripelennamine;Brompheniramine-d6 maleate;Hypericin;Samelisant;Chlorphenoxamine;H3 receptor-MO-1;Diphenhydramine;ABT-239;Galeterone;Ketotifen fumarate;Ranitidine;BD1063 dhydrochloride;Bergapten;Ginsenoside Rd;Cetirizine;AS1810722;Diphenylpyraline hydrochloride Trending […]

For research use only. We do not sell to patients. γ-Secretase modulator 12 CAS No. : 2204249-82-9 Biological Activity：γ-Secretase modulator 12 (Compound 1a) is a γ-secretase modulator that can selectively decrease amyloid-β42 (Aβ42) levels (IC50 of 0.39 µM). γ-Secretase modulator 12 can be used for Alzheimer’s disease research. γ-Secretase modulator 12 has a good brain/plasma […]

For research use only. We do not sell to patients. Palmatine CAS No. : 3486-67-7 Biological Activity：Palmatine is an orally active and irreversible indoleamine 2,3-dioxygenase 1 (IDO-1) inhibitor with IC50s of 3 μM and 157μM against HEK 293-hIDO-1 and rhIDO-1, respectively. Palmatine can also inhibit West Nile virus (WNV) NS2B-NS3 protease in an uncompetitive manner […]

For research use only. We do not sell to patients. Atazanavir sulfate CAS No. : 229975-97-7 Biological Activity：Atazanavir (BMS-232632) sulfate, a highly selective HIV-1 protease inhibitor, is the first protease inhibitor approved for once-daily administration. Atazanavir sulfate is a substrate and inhibitor of CYP3A4, and an inhibitor and inducer of P-glycoprotein (P-gp)[2]. Atazanavir sulfate is […]

For research use only. We do not sell to patients. Thevetiaflavone CAS No. : 29376-68-9 Biological Activity：Thevetiaflavone could upregulate the expression of Bcl‑2 and downregulate that of Bax and caspase‑3. Research Area：Neurological Disease Targets：Bcl-2 Family|Caspase Related Small Molecules:BI-3812;Pyridoclax;PUMA BH3 TFA;Dehydrocorydaline;Z-DEVD-AMC;Bufarenogin;Murizatoclax;p-nitro-Pifithrin-α;Obatoclax;ML132;CYD-2-11;BM 957;L67;AKN-028 acetate;(S)-Gossypol (acetic acid);Ossirene;A-385358;Mcl-1 inhibitor 6;S55746;δ-Secretase inhibitor 11;Anticancer agent 63;Fenbufen-d9;MCL-1/BCL-2-IN-2;Penicillic acid;Anticancer agent 65;Sesamolin;(E)-Ferulic acid-d3 Trending […]

For research use only. We do not sell to patients. DCPIB CAS No. : 82749-70-0 Biological Activity：DCPIB is a selective, reversible and potent inhibitor of volume-regulated anion channels (VRAC). DCPIB voltage-dependently activates potassium channels TREK1 and TRAAK, and inhibits TRESK, TASK1 and TASK3 (IC50s: 0.14, 0.95, 50.72 μM, respectively). DCPIB is also a selective blocker […]