Tag: Antagonist|Inhibitor|Activator

For research use only. We do not sell to patients. Prochloraz CAS No. : 67747-09-5 Biological Activity：Prochloraz is an imidazole antifungal. Prochloraz is as an estrogen receptor (ER) and androgen receptor (AR) antagonist and an aromatase inhibitor with IC50 values of 25 μM, 4 μM and 0.3 μM, respectively. Prochloraz is able to activate the […]

For research use only. We do not sell to patients. MK-886 CAS No. : 118414-82-7 Biological Activity：MK-886 (L 663536) is a potent, cell-permeable and orally active FLAP (IC50 of 30 nM) and leukotriene biosynthesis (IC50s of 3 nM and 1.1 μM in intact leukocytes and human whole blood, respectively) inhibitor. MK-886 is also a non-competitive […]

For research use only. We do not sell to patients. Topiramate CAS No. : 97240-79-4 Biological Activity：Topiramate (McN 4853) is a broad-spectrum antiepileptic agent. Topiramate is a GluR5 receptor antagonist. Topiramate produces its antiepileptic effects through enhancement of GABAergic activity, inhibition of kainate/AMPA receptors, inhibition of voltage-sensitive sodium and calcium channels, increases in potassium conductance, […]

For research use only. We do not sell to patients. Mifepristone CAS No. : 84371-65-3 Biological Activity：Mifepristone (RU486) is a progesterone receptor (PR) and glucocorticoid receptor (GR) antagonist with IC50s of 0.2 nM and 2.6 nM in in vitro assay. Research Area：Endocrinology|Cancer Targets：Autophagy|Glucocorticoid Receptor|Progesterone Receptor|NO Synthase Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library […]

For research use only. We do not sell to patients. EIPA hydrochloride CAS No. : 1345839-28-2 Biological Activity：EIPA (L593754) hydrochloride is an orally active TRPP3 channel inhibitor with an IC50 of 10.5 μM. EIPA hydrochloride also enhances autophagy by inhibiting Na+/H+-exchanger 3 (NHE3). EIPA hydrochloride inhibits macropinocytosis as well. EIPA hydrochloride can be used in […]

For research use only. We do not sell to patients. Topiramate D12 CAS No. : 1279037-95-4 Biological Activity：Topiramate D12 (McN 4853 D12) is a deuterium labeled Topiramate. Topiramate is a broad-spectrum antiepileptic agent. Topiramate is a GluR5 receptor antagonist. Topiramate produces its antiepileptic effects through enhancement of GABAergic activity, inhibition of kainate/AMPA receptors, inhibition of […]

For research use only. We do not sell to patients. IMM-H007 CAS No. : 1221412-23-2 Biological Activity：IMM-H007 (WS070117) is an orally active and potent AMPK (AMP-activated protein kinase) activator and TGFβ1 (transforming growth factor β1) antagonist. IMM-H007 has protective effects in cardiovascular diseases via activation of AMPK. IMM-H007 negatively regulates endothelium inflammation through inactivating NF-κB […]

For research use only. We do not sell to patients. Topiramate lithium CAS No. : 488127-53-3 Biological Activity：Topiramate (McN 4853) lithium is a broad-spectrum antiepileptic agent. Topiramate lithium is a GluR5 receptor antagonist. Topiramate produces its antiepileptic effects through enhancement of GABAergic activity, inhibition of kainate/AMPA receptors, inhibition of voltage-sensitive sodium and calcium channels, increases […]