Topiramate D12

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Topiramate D12

CAS No. : 1279037-95-4

Biological Activity:Topiramate D12 (McN 4853 D12) is a deuterium labeled Topiramate. Topiramate is a broad-spectrum antiepileptic agent. Topiramate is a GluR5 receptor antagonist. Topiramate produces its antiepileptic effects through enhancement of GABAergic activity, inhibition of kainate/AMPA receptors, inhibition of voltage-sensitive sodium and calcium channels, increases in potassium conductance, and inhibition of carbonic anhydrase[2][3].

Research Area:Neurological Disease

Targets:Calcium Channel|Sodium Channel|Potassium Channel|Carbonic Anhydrase|GABA Receptor|iGluR

Related Small Molecules:SKF89976A hydrochloride;Enpp/Carbonic anhydrase-IN-1;Benidipine hydrochloride;Lu AE98134;CaV1.3 antagonist-1;14-Deoxyandrographolide;hCAIX-IN-8;Kv3 modulator 2;Zandatrigine;mGAT-IN-1;CIQ;(Rac)-MEM 1003;Quinolinic acid-d3;Glaucine;Veratridine;Efonidipine hydrochloride monoethanolate;L-Ascorbic acid sodium salt;Brompheniramine-d6 maleate;Pinacidil;MRS 1523;GX-674;Nilvadipine;Alpidem;1-Aminocyclobutanecarboxylic acid;Glycine-1-13C,15N

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