Tag: Agonist|Inducer

For research use only. We do not sell to patients. Loperamide-d6 N-Oxide CAS No. : 1329835-39-3 Biological Activity：Loperamide-d6 N-Oxide is the deuterium labeled Loperamide hydrochloride. Loperamide hydrochloride (R-18553 hydrochloride) is an opioid receptor agonist[2][3]. Loperamide hydrochloride is a selective and competitive human intestinal carboxylesterases (hiCE) inhibitor. Loperamide hydrochloride has anti-diarrheal effect[4]. Research Area：Metabolic Disease|Neurological Disease […]

For research use only. We do not sell to patients. Cabergoline-d5 CAS No. : 1426173-20-7 Biological Activity：Cabergoline-d5 (FCE-21336-d5) is the deuterium labeled Cabergoline. Cabergoline is an ergot derived-dopamine D2-like receptor agonist that has high affinity for D2, D3, and 5-HT2B receptors (Ki=0.7, 1.5, and 1.2, respectively)[2]. Research Area：Endocrinology Targets：Dopamine Receptor|Autophagy Related Small Molecules:Alizapride hydrochloride;Thioproperazine;Bromopride-d3;Nuciferine;Glaucine;SB-277011 dihydrochloride;MIF-1 […]

For research use only. We do not sell to patients. CYD-2-11 CAS No. : 1425944-22-4 Biological Activity：CYD-2-11 is a selective Bax agonist with a Ki value of 34.1 nM. CYD-2-11 induces cell apoptosis and shows antiproliferative activity to breast cancer MDA-MB-231 and MCF-7 cell lines with IC50 values of 3.22 and 3.81 μM, respectively. CYD-2-11 […]

For research use only. We do not sell to patients. TIC10 CAS No. : 1616632-77-9 Biological Activity：TIC10 (ONC-201) is a potent, orally active, and stable tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) inducer which acts by inhibiting Akt and ERK, consequently activating Foxo3a and significantly inducing cell surface TRAIL. TIC10 can cross the blood-brain barrier. Research […]

For research use only. We do not sell to patients. Buspirone hydrochloride CAS No. : 33386-08-2 Biological Activity：Buspirone hydrochloride is a 5-HT1A receptor agonist. Buspirone hydrochloride can be used for anxiety and depression research[2]. Research Area：Cancer|Neurological Disease Targets：5-HT Receptor|Reactive Oxygen Species Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound […]

For research use only. We do not sell to patients. Loperamide hydrochloride CAS No. : 34552-83-5 Biological Activity：Loperamide (hydrochloride) (R-18553 (hydrochloride)) is an opioid receptor agonist[2][3]. Loperamide hydrochloride is a selective and competitive human intestinal carboxylesterases (hiCE) inhibitor. Loperamide hydrochloride has anti-diarrheal effect[4]. Research Area：Metabolic Disease|Neurological Disease|Cancer Targets：Opioid Receptor|Autophagy Related Screening Libraries:Drug Repurposing Compound Library […]

For research use only. We do not sell to patients. Adapalene-d6 Methyl Ester CAS No. : 1330264-23-7 Biological Activity：Adapalene-d6 Methyl Ester is the deuterium labeled Adapalene. Adapalene (CD271), a third-generation synthetic retinoid, is widely used for the research of acne. Adapalene is a potent RAR agonist, with AC50s of 2.3 nM, 9.3 nM, and 22 […]

For research use only. We do not sell to patients. Avadomide CAS No. : 1015474-32-4 Biological Activity：Avadomide (CC 122) is an orally active cereblon modulator. Avadomide modulates cereblon E3 ligase activity and induces apoptosis of diffuse large B-cell lymphoma (DLBCL) cell lines. Avadomide exhibits potent antitumor and immunomodulatory activities[2]. Research Area：Cancer|Inflammation/Immunology Targets：Apoptosis|E1/E2/E3 Enzyme|Molecular Glues Related […]

For research use only. We do not sell to patients. Norepinephrine hydrochloride CAS No. : 329-56-6 Biological Activity：Norepinephrine (Levarterenol; L-Noradrenaline) hydrochloride is a potent adrenergic receptor (AR) agonist. Norepinephrine activates α1, α2, β1 receptors[2][3][4]. Research Area：Cardiovascular Disease|Endocrinology|Cancer Targets：Adrenergic Receptor|Autophagy|Endogenous Metabolite Related Screening Libraries:Natural Product Library Plus;Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library […]

For research use only. We do not sell to patients. Prednisone-d8 Biological Activity：Prednisone-d8 (Dehydrocortisone-d8) is the deuterium labeled Prednisone. Prednisone (Adasone) is a synthetic corticosteroid agent that is particularly effective as an immunosuppressant compound. Research Area：Inflammation/Immunology|Endocrinology|Cancer Targets：Glucocorticoid Receptor|Apoptosis Related Small Molecules:Physalin A;Bomedemstat ditosylate;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;Xevinapant;Mangiferin;Cambinol;Antioxidant agent-5;Apoptosis inducer 9;Bafetinib;Deflazacort-D5;Cyclovirobuxine D Trending products：Recombinant Proteins  […]