Tag: Agonist|Inhibitor|Activator

For research use only. We do not sell to patients. EDP-305 CAS No. : 1933507-63-1 Biological Activity：EDP-305 is an orally active, potent and selective farnesoid X receptor (FXR) agonist, with EC50 values of 34 nM (chimeric FXR in CHO cells) and 8 nM (full-length FXR in HEK cells). EDP-305 shows a potent and consistent antifibrotic […]

For research use only. We do not sell to patients. CALP1 CAS No. : 145224-99-3 Biological Activity：CALP1 is a calmodulin (CaM) agonist (Kd of 88 µM) with binding to the CaM EF-hand/Ca2+-binding site. CALP1 blocks calcium influx and apoptosis (IC50 of 44.78 µM) through inhibition of calcium channel opening. CALP1 blocks glutamate receptor channels and […]

For research use only. We do not sell to patients. Vesatolimod CAS No. : 1228585-88-3 Biological Activity：Vesatolimod (GS-9620) is a potent, selective and orally active agonist of Toll-Like Receptor (TLR7) with an EC50 of 291 nM. Research Area：Inflammation/Immunology Targets：HCV|HIV|HBV|Toll-like Receptor (TLR)|Apoptosis Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Anti-Infection Compound […]

For research use only. We do not sell to patients. Imiquimod maleate CAS No. : 896106-16-4 Biological Activity：Imiquimod maleate (R 837 maleate), an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist. Imiquimod maleate exhibits antiviral and antitumor effects in vivo. Imiquimod maleate can be used for the research of external genital, […]

For research use only. We do not sell to patients. Resveratrol analog 2 CAS No. : 915378-82-4 Biological Activity：Resveratrol analog 2 is an analog of Resveratrol (HY-16561). Resveratrol is a natural polyphenolic phytoalexin that possesses anti-oxidant, anti-inflammatory, cardioprotective, and anti-cancer properties. Research Area：Cancer|Inflammation/Immunology Targets：Autophagy|Mitophagy|IKK|Sirtuin Related Small Molecules:PROTAC Sirt2 Degrader-1;SIRT1/2/3-IN-1;Cambinol;Curcumin;JGB1741;Melatonin-d3;Nicotinamide-d4;PS-1145;NF-κB-IN-1;Sirtuin modulator 3;Resveratrol;SRT 1720 Hydrochloride;Clioquinol;IKK-IN-3;Sirtuin modulator 2;SIRT1-IN-3;SRT 2104;Anti-inflammatory […]

For research use only. We do not sell to patients. Imiquimod hydrochloride CAS No. : 99011-78-6 Biological Activity：Imiquimod hydrochloride (R 837 hydrochloride), an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist. Imiquimod hydrochloride exhibits antiviral and antitumor effects in vivo. Imiquimod hydrochloride can be used for the research of external genital, […]

For research use only. We do not sell to patients. RO8191 CAS No. : 691868-88-9 Biological Activity：RO8191 (CDM-3008), an imidazonaphthyridine compound, is an orally active and potent interferon (IFN) receptor agonist. RO8191 directly binds to IFNα/β receptor 2 (IFNAR2) and activates IFN-stimulated genes (ISGs) expression and JAK/STAT phosphorylation. RO8191 shows antiviral activity against both HCV […]

For research use only. We do not sell to patients. Imiquimod CAS No. : 99011-02-6 Biological Activity：Imiquimod (R 837), an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist. Imiquimod exhibits antiviral and antitumor effects in vivo. Imiquimod can be used for the research of external genital, perianal warts, cancer and COVID-19[2]. […]

For research use only. We do not sell to patients. CALP1 TFA Biological Activity：CALP1 TFA is a calmodulin (CaM) agonist (Kd of 88 µM) with binding to the CaM EF-hand/Ca2+-binding site. CALP1 TFA blocks calcium influx and apoptosis (IC50 of 44.78 µM) through inhibition of calcium channel opening. CALP1 TFA blocks glutamate receptor channels and […]