Tag: Inducer|Antagonist

For research use only. We do not sell to patients. Ro 41-5253 CAS No. : 144092-31-9 Biological Activity：Ro 41-5253 is an orally active selective retinoic acid receptor alpha (RARα) antagonist. Ro 41-5253 can bind RARα without inducing transcription or affecting RAR/RXR heterodimerization and DNA binding. Ro 41-5253 can inhibit cancer cell proliferation and induce apoptosis, […]

For research use only. We do not sell to patients. Azilsartan CAS No. : 147403-03-0 Biological Activity：Azilsartan (TAK-536) is an orally active, potent, selective and specific angiotensin II type 1 receptor (AT1) antagonist. Azilsartan induces ROS formation and apoptosis in HepG2 cells. Azilsartan shows neuroprotective and anticancer activity. Azilsartan can be used for hypertension and […]

For research use only. We do not sell to patients. (E)-Cardamonin CAS No. : 19309-14-9 Biological Activity：(E)-Cardamonin ((E)-Cardamomin) is a novel antagonist of hTRPA1 cation channel with an IC50 of 454 nM. Research Area：Neurological Disease|Cancer Targets：TRP Channel|Apoptosis Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus;Apoptosis Compound Library;Membrane Transporter/Ion Channel Compound Library;Neuronal Signaling Compound Library;Natural […]

For research use only. We do not sell to patients. Irbesartan CAS No. : 138402-11-6 Biological Activity：Irbesartan (SR-47436) is an orally active Ang II type 1 (AT1) receptor blocker (ARB). Irbesartan can relax the blood vessels, low blood pressure and increase the supply of blood and oxygen to the heart. Irbesartan can be used for […]

For research use only. We do not sell to patients. Fulvestrant CAS No. : 129453-61-8 Biological Activity：Fulvestrant (ICI 182780) is a pure antiestrogen and a potent estrogen receptor (ER) antagonist with an IC50 of 9.4 nM. Fulvestrant is also a GPR30 agonist. Fulvestrant effectively inhibits the growth of ER-positive MCF-7 cells with an IC50 of […]

For research use only. We do not sell to patients. AZD5582 dihydrochloride CAS No. : 1883545-51-4 Biological Activity：AZD5582 dihydrochloride is an antagonist of the inhibitor of apoptosis proteins (IAPs), which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively. AZD5582 induces apoptosis. Research Area：Cancer Targets：IAP|Apoptosis Related […]

For research use only. We do not sell to patients. MV1 CAS No. : 1001600-54-9 Biological Activity：MV1 is an antagonist of IAP (inhibitor of apoptosis protein), leads to protein knockdown of HaloTag-fused proteins when combined with HaloTag ligand. Research Area：Cancer Targets：IAP|Apoptosis Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;Anti-Cancer Compound Library;Anti-Prostate Cancer Compound Library; Related […]

For research use only. We do not sell to patients. UNBS5162 CAS No. : 956590-23-1 Biological Activity：UNBS5162 is a pan-antagonist of CXCL chemokine expression, with anti-tumor activity. Research Area：Cancer|Endocrinology Targets：CXCR|Autophagy Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Immunology/Inflammation Compound Library;Anti-Cancer Compound Library;Autophagy Compound Library;Small Molecule Immuno-Oncology Compound Library;Endocrinology Compound Library;Chemokine Compound Library; Related Small […]

For research use only. We do not sell to patients. Nifedipine-d4 CAS No. : 1219798-99-8 Biological Activity：Nifedipine-d4 (BAY-a-1040-d4) is the deuterium labeled Nifedipine. Nifedipine (BAY-a-1040) is a potent calcium channel blocker and drug of choice for cardiac insufficiencies. Research Area：Cardiovascular Disease|Cancer Targets：Autophagy|Calcium Channel Related Small Molecules:Benidipine hydrochloride;CaV1.3 antagonist-1;14-Deoxyandrographolide;(Rac)-MEM 1003;Glaucine;Efonidipine hydrochloride monoethanolate;L-Ascorbic acid sodium salt;Brompheniramine-d6 maleate;MRS […]

For research use only. We do not sell to patients. Degarelix acetate hydrate CAS No. : 934246-14-7 Biological Activity：Degarelix acetate hydrate is a competitive and reversible gonadotropin-releasing hormone receptor (GnRHR/LHRHR) antagonist. Degarelix acetate hydrate can be used for prostate cancer research. Research Area：Cancer|Endocrinology Targets：GnRH Receptor|Apoptosis Related Small Molecules:Physalin A;Bomedemstat ditosylate;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;Xevinapant;Mangiferin;Cambinol;Antioxidant […]