Tag: Modulator|Agonist

For research use only. We do not sell to patients. Pindolol-d7 CAS No. : 1185031-19-9 Biological Activity：Pindolol-d7 (LB-46-d7) is the deuterium labeled Pindolol. Pindolol (LB-46) is a nonselective β-blocker with partial beta-adrenergic receptor agonist activity, also functions as a 5-HT1A receptor weak partial antagonist (Ki=33 nM)[2]. Research Area：Neurological Disease|Endocrinology Targets：Adrenergic Receptor|5-HT Receptor Related Small Molecules:F […]

For research use only. We do not sell to patients. Brilaroxazine CAS No. : 1239729-06-6 Biological Activity：Brilaroxazine (RP5603) is a potent and orally active multimodal dopamine (DA)/serotonin (5-HT) modulator. Brilaroxazine is a partial agonist of dopamine (DA) D2, D3, and D4 receptors, 5-HT1A (Ki=1.5 nM) and 5-HT2A (Ki=2.5 nM), and has antagonist activity at 5-HT2B (Ki=0.19 nM), […]

For research use only. We do not sell to patients. Brexpiprazole CAS No. : 913611-97-9 Biological Activity：Brexpiprazole (OPC-34712), an atypical orally active antipsychotic drug, is a partial agonist of human 5-HT1A and dopamine D2L receptor with Kis of 0.12 nM and 0.3 nM, respectively. Brexpiprazole is also a 5-HT2A receptor antagonist with a Ki of […]

For research use only. We do not sell to patients. MSDC-0602K CAS No. : 1314533-27-1 Biological Activity：MSDC-0602K (Azemiglitazone potassium), a PPARγ-sparing thiazolidinedione (Ps-TZD), binds to PPARγ with the IC50 of 18.25 μM. MSDC-0602K modulates the mitochondrial pyruvate carrier (MPC). MSDC-0602K can be used for the research of fatty liver including dysfunctional lipid metabolism, inflammation, and […]

For research use only. We do not sell to patients. Brexpiprazole-d8 CAS No. : 1427049-21-5 Biological Activity：Brexpiprazole D8 (OPC-34712 D8) is a deuterium labeled Brexpiprazole (OPC-34712). Brexpiprazole, an atypical antipsychotic drug, is a partial agonist of human 5-HT1A and dopamine receptor (Ki=0.12 nM and 0.3 nM, respectively). Brexpiprazole is also a 5-HT2A receptor antagonist (Ki=0.47 […]

For research use only. We do not sell to patients. Brexpiprazole hydrochloride CAS No. : 913612-38-1 Biological Activity：Brexpiprazole (OPC-34712) hydrochloride, an atypical orally active antipsychotic drug, is a partial agonist of human 5-HT1A and dopamine D2L receptor with Kis of 0.12 nM and 0.3 nM, respectively. Brexpiprazole hydrochloride is also a 5-HT2A receptor antagonist with […]

For research use only. We do not sell to patients. UNC9994 hydrochloride CAS No. : 2108826-33-9 Biological Activity：UNC9994 hydrochloride is a functionally selective, β-arrestin–biased dopamine D2 receptor (D2R) agonist that selectively activates β-arrestin recruitment and signaling. UNC9994 hydrochloride shows a binding affinity with a Ki of 79 nM for D2R. UNC9994 hydrochloride is also an […]