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MSDC-0602K
CAS No. : 1314533-27-1
Biological Activity：MSDC-0602K (Azemiglitazone potassium), a PPARγ-sparing thiazolidinedione (Ps-TZD), binds to PPARγ with the IC50 of 18.25 μM. MSDC-0602K modulates the mitochondrial pyruvate carrier (MPC). MSDC-0602K can be used for the research of fatty liver including dysfunctional lipid metabolism, inflammation, and insulin resistance[2]. MSDC-0602K, an insulin sensitizer, improves insulinemia and fatty liver disease in mice, alone and in combination with Liraglutide[3].
Research Area：Metabolic Disease
Targets：Insulin Receptor|PPAR
Related Small Molecules:Falcarindiol;5-Aminosalicylic Acid-D3 hydrochloride;Retinoic acid;AGL-2263;PPARγ agonist 7;Licarin B;Mifobate;Daidzein-d4;Ciglitazone;MK-886;CP-775146;KU14R;FK614;Muraglitazar;Magnolol;SU4984;PPAR agonist 1;PPARα agonist 1;PPARγ phosphorylation inhibitor 1;GSK0660;Glabridin;CUDA
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