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UNC9994 hydrochloride

CAS No. : 2108826-33-9

Biological Activity：UNC9994 hydrochloride is a functionally selective, β-arrestin–biased dopamine D₂ receptor (D₂R) agonist that selectively activates β-arrestin recruitment and signaling. UNC9994 hydrochloride shows a binding affinity with a K_i of 79 nM for D₂R. UNC9994 hydrochloride is also an antagonist of G_i-regulated cAMP production and partial agonist for D2R/β-arrestin-2 interactions. UNC9994 hydrochloride shows antipsychotic-like activity.

Research Area：Neurological Disease

Targets：Dopamine Receptor|5-HT Receptor

Related Screening Libraries:Bioactive Compound Library Plus;

Related Small Molecules:F 13714;Alizapride hydrochloride;Thioproperazine;Mosapride-d5;Bromopride-d3;Nuciferine;Glaucine;Renzapride;SB-277011 dihydrochloride;LY 344864 racemate;Harmine hydrochloride;MIF-1 TFA;Valerenic acid;Arotinolol;Sulpiride;(Rac)-Razpipadon;Melitracen-d6 hydrochloride;Clebopride malate;WAY-100635;Nelotanserin;Flupentixol-d4 dihydrochloride

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