Master of Bioactive Molecules | Inhibitors, Screening Libraries & Proteins
For research use only. We do not sell to patients. Enitociclib CAS No. : 1610358-56-9 Biological Activity：Enitociclib ((+)-Enitociclib) is an enanthiomer of BAY-1251152 with rotation (+). Enitociclib is a potent and selective CDK9 inhibitor with an IC50 of 3 nM. Enitociclib has anti-tumour activity[2]. Research Area：Cancer Targets：CDK Related Screening Libraries:Bioactive Compound Library Plus;Cell Cycle/DNA Damage […]
For research use only. We do not sell to patients. CB2 receptor antagonist 1 CAS No. : 2772693-05-5 Biological Activity：Hexyl resorcinol derivative 29 has been proved to be a CB2 selective competitive antagonist / reverse agonist with good potency. Olivanol and 5- (2-methyloctane-2-yl) resorcinol derivatives 23 and 24 showed significant antinociceptive activity. Compound 24 was […]
For research use only. We do not sell to patients. PKR activator 1 CAS No. : 2283420-62-0 Biological Activity：PKR activator 1 is a potent pyruvate kinase-R (PKR) activator extracted from patent WO2019035865A1, compound E7-93. Research Area：Cardiovascular Disease Targets：Pyruvate Kinase Related Small Molecules:TEPP-46;Etavopivat;Alkannin;PKM2-IN-3;PKM2-IN-1;PKM2 activator 3;PKR-IN-2;PKR activator 2;PKM2 activator 5;Mitapivat;FX-11;PKM2 activator 4;DASA-58;TEPC466;PKM2 activator 2 Trending products：Recombinant Proteins […]
For research use only. We do not sell to patients. PT2399 CAS No. : 1672662-14-4 Biological Activity：PT2399 is a potent and selective HIF-2α antagonist, which directly binds to HIF-2α PAS B domain with an IC50 of 6 nM. PT2399 displays potent antitumor activity in vivo[2][3]. Research Area：Cancer Targets：HIF/HIF Prolyl-Hydroxylase Related Screening Libraries:Bioactive Compound Library Plus; […]
For research use only. We do not sell to patients. Vutrisiran CAS No. : 1867157-35-4 Biological Activity：Vutrisiran (ALN-TTRsc02) is a liver-directed, investigational, small interfering ribonucleic acid (siRNA) agent. Vutrisiran can be used for transthyretin (TTR)-mediated amyloidosis research. Research Area：Neurological Disease Targets：Transthyretin (TTR)|Small Interfering RNA (siRNA) Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;Bioactive […]
For research use only. We do not sell to patients. Wnt/β-catenin agonist 2 CAS No. : 943820-93-7 Biological Activity：Wnt/β-catenin agonist 2 is a potent Wnt agonist. Wnt/β-catenin agonist 2 activates Wnt/β-catenin signaling and can be used in the research of diseases related to the signal transduction. (From patent WO2007078113A1, compound 39) Research Area：Others Targets：β-catenin Related […]
For research use only. We do not sell to patients. Buparlisib CAS No. : 944396-07-0 Biological Activity：Buparlisib (BKM120; NVP-BKM120) is a pan-class I PI3K inhibitor, with IC50s of 52, 166, 116 and 262 nM for p110α, p110β, p110δ and p110γ, respectively. Research Area：Cancer Targets：Apoptosis|PI3K Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound […]
For research use only. We do not sell to patients. Ozagrel CAS No. : 82571-53-7 Biological Activity：Ozagrel (OKY-046)is an anti-asthmatic agent and a thromboxane A2 (TXA2) synthase inhibitor. Ozagrel is an antiplatelet agent, which selectively inhibits human platelet aggregation with an IC50 of 53.12 μM. Research Area：Cardiovascular Disease Targets：Prostaglandin Receptor Related Screening Libraries:Drug Repurposing Compound […]
For research use only. We do not sell to patients. Fulvestrant-9-sulfone-d3 Biological Activity：Fulvestrant-9-sulfone-d3 is the deuterium labeled Fulvestrant-9-sulfone. Research Area：Others Targets：Others Related Small Molecules:Immune initiator-1;Obiltoxaximab;DIBAC-GGFG-NH2CH2-Dxd;Cyanine5.5 maleimide chloride;Cymarin;Z-Glycine;2-Deoxy-2-fluoro-D-glucose-13C,d7;Water-18O;Fmoc-N-Me-D-Ala-OH;3,5-Diiodo-L-tyrosine;N3-Pen-Dde;Zimeldine-d6;Ornidazole diol;Nylidrin hydrochloride;PFI-653;N-Arachidonoyl Taurine-d4;OVA Peptide (323-339);((3-Fluorophenyl)sulfonyl)glycine;7ß-Hydroxycholesterol-d7;MALAT1-IN-1;Sibiricose A1;Mefruside-d3;Ethacrynic acid mercapturate-d3;FLAG peptide;Neocurdione Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | […]
For research use only. We do not sell to patients. KN-93 hydrochloride CAS No. : 1956426-56-4 Biological Activity：KN-93 hydrochloride is a cell-permeable, reversible and competitive inhibitor calmodulin-dependent kinase type II (CaMKII) with a Ki of 370 nM. Research Area：Cancer Targets：Autophagy|CaMK Related Screening Libraries:Bioactive Compound Library Plus;Kinase Inhibitor Library;Neuronal Signaling Compound Library;Anti-Cancer Compound Library;Autophagy Compound Library; […]