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CAS No. : 1672662-14-4
Biological Activity：PT2399 is a potent and selective HIF-2α antagonist, which directly binds to HIF-2α PAS B domain with an IC50 of 6 nM. PT2399 displays potent antitumor activity in vivo.
Related Screening Libraries:Bioactive Compound Library Plus; Epigenetics Compound Library;Immunology/Inflammation Compound Library;Metabolism/Protease Compound Library;Anti-Cancer Compound Library;Oxygen Sensing Compound Library;Chemical Probe Library;Glutamine Metabolism Compound Library;Anti-Breast Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Angiogenesis-Related Compound Library;Transcription Factor-Targeted Library;Targeted Diversity Library;Cancer Stem Cells Compound Library;
Related Small Molecules:TC-S 7009;Glucosamine-13C hydrochloride;HIF1-IN-3;Prolyl Hydroxylase inhibitor 1;Glucosamine-13C6,15N hydrochloride;HIF-PHD-IN-1;AKBA;LW6;HIF-2α-IN-5;HIF-1/2α-IN-2;GEM-5;HIF-1/2α-IN-1;Roxadustat;Daprodustat;Acetylarenobufagin;Zifcasiran;Acriflavine hydrochloride;BAY 87-2243;PHD-1-IN-1;PT-2385;ZINC13466751;(Rac)-Dencichine;Enarodustat;HIF-2α-IN-6;ENMD-1198
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