Category: Reference compound

For research use only. We do not sell to patients. Britannilactone diacetate CAS No. : 1286694-67-4 Biological Activity：Britannilactone diacetate (1,6-O,O-Diacetylbritannilactone; Compound 2) exhibits potential NO inhibition effect. Britannilactone diacetate exhibits activity against NO production induced by LPS in BV-2 microglial cells with the EC50 value of 6.3 μM. Britannilactone diacetate exhibits a favorable blood-brain barriers (BBB) penetration and absorption, distribution, […]

For research use only. We do not sell to patients. ZL-Pin13 Biological Activity：ZL-Pin13 is a high potent cell-active covalent inhibitor targeting the Pin1 (Peptidyl-Prolyl Isomerase NIMA-Interacting-1) with an IC50 of 67 nM. ZL-Pin13 effectively inhibits the proliferation and downregulated the Pin1 substrates in MDA-MB-231 cells. Research Area：Cancer Targets：Others Related Small Molecules:Immune initiator-1;Obiltoxaximab;DIBAC-GGFG-NH2CH2-Dxd;Cyanine5.5 maleimide chloride;Cymarin;Z-Glycine;2-Deoxy-2-fluoro-D-glucose-13C,d7;Water-18O;Fmoc-N-Me-D-Ala-OH;3,5-Diiodo-L-tyrosine;N3-Pen-Dde;Zimeldine-d6;Ornidazole diol;Nylidrin […]

For research use only. We do not sell to patients. Tebipenem pivoxil CAS No. : 161715-24-8 Biological Activity：Tebipenem pivoxil (L084) is an orally active antibiotic against a variety of pathogenic bacteria. Tebipenem pivoxil binds penicillin-binding protein (PBP), thereby inhibiting cell wall synthesis. Research Area：Infection Targets：Bacterial|Antibiotic Related Screening Libraries:Covalent Screening Library Plus;Natural Product-like Compound Library;Drug Repurposing […]

For research use only. We do not sell to patients. DC-LC3in-D5 Biological Activity：DC-LC3in-D5 acts as an autophagy inhibitor by attenuating LC3B lipidation. DC-LC3in-D5 binds with LC3B. DC-LC3in-D5 disrupts the LC3B-LBP2 interaction with an IC50 of 200 nM. DC-LC3in-D5 may contribute to anti-HCV or combination treatments in cancer through inhibiting autophagy. Research Area：Cancer|Infection|Inflammation/Immunology Targets：Autophagy Related Screening […]

For research use only. We do not sell to patients. GSK461364 CAS No. : 929095-18-1 Biological Activity：GSK461364 is a selective, reversible and ATP-competitive Polo-like kinase 1 (PLK1) inhibitor with a Ki value of 2.2 nM. Research Area：Cancer Targets：Polo-like Kinase (PLK) Related Screening Libraries:Clinical Compound Library Plus;Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;Kinase Inhibitor Library;Anti-Cancer […]

For research use only. We do not sell to patients. PROTAC BRD4 Degrader-2 CAS No. : 2185795-53-1 Biological Activity：PROTAC BRD4 Degrader-2 is a PROTAC connected by ligands for Cereblon and BRD4 with an IC50 of 14.2 nM against BRD4 BD1. Research Area：Cancer Targets：Epigenetic Reader Domain|PROTACs Related Small Molecules:PROTAC Sirt2 Degrader-1;DB0614;RVX-297;BRD4 Inhibitor-19;UNC6349 (Ket2);PROTAC VEGFR-2 degrader-2;Curcumin;GSK6853;dTAGV-1-NEG;CCT367766 formic;GSK4028;SR-0813;HDAC6 […]