Reference compound - epigenetics modulation frontier

SJM-3

Posted on December 26, 2022 by haoyuan2014

For research use only. We do not sell to patients. SJM-3 CAS No. : 1234977-97-9 Biological Activity：SJM-3 is a positive allosteric modulator of different isoforms of the GABAA receptor. SJM-3 binds at the high-affinity benzodiazepine binding site at the α+/γ- subunit interface. Research Area：Neurological Disease Targets：GABA Receptor Related Small Molecules:SKF89976A hydrochloride;mGAT-IN-1;Alpidem;FG8119;Valerenic acid;Picrotoxinin;Miltirone;Etifoxine-13C,d3;Adipiplon;Gabazine;Broflanilide;Fluxametamide;ONO-8590580;γ-Aminobutyric acid-d6;Ginsenoside Rc;Fipronil;p-Hydroxybenzaldehyde-13C;Lesogaberan hydrochloride;FG […]

DRB18

Posted on December 26, 2022 by haoyuan2014

For research use only. We do not sell to patients. DRB18 Biological Activity：DRB18 is a potent pan-class GLUT inhibitor. DRB18 alters energy-related metabolism in A549 cells by changing the abundance of metabolites in glucose-related pathways. DRB18 can eventually lead to G1/S phase arrest and increase oxidative stress and necrotic cell death. DRB18 has anti-tumor activity. […]

Imiclopazine

Posted on December 26, 2022 by haoyuan2014

For research use only. We do not sell to patients. Imiclopazine CAS No. : 7414-95-1 Biological Activity：Imiclopazine is a phenothiazine derivative with with psychomotor stabilizing properties, antiaggressive and antiemetic effects. Research Area：Neurological Disease Targets：Others Related Small Molecules:Immune initiator-1;Obiltoxaximab;DIBAC-GGFG-NH2CH2-Dxd;Cyanine5.5 maleimide chloride;Cymarin;Z-Glycine;2-Deoxy-2-fluoro-D-glucose-13C,d7;Water-18O;Fmoc-N-Me-D-Ala-OH;3,5-Diiodo-L-tyrosine;N3-Pen-Dde;Zimeldine-d6;Ornidazole diol;Nylidrin hydrochloride;PFI-653;N-Arachidonoyl Taurine-d4;OVA Peptide (323-339);((3-Fluorophenyl)sulfonyl)glycine;7ß-Hydroxycholesterol-d7;MALAT1-IN-1;Sibiricose A1;Mefruside-d3;Ethacrynic acid mercapturate-d3;FLAG peptide;Neocurdione Trending products：Recombinant Proteins | Bioactive Screening […]

Antitubercular agent-10

Posted on December 26, 2022 by haoyuan2014

For research use only. We do not sell to patients. Antitubercular agent-10 CAS No. : 2679830-78-3 Biological Activity：Antitubercular agent-10 shows potent antitubercular activity with a MIC value of 30 nM. Research Area：Infection Targets：Bacterial Related Small Molecules:Sandramycin;LLO (91-99);Gepotidacin;Oritavancin;Azlocillin sodium salt;Herbimycin A;Antibacterial agent 45;Leucomycin;Isouvaretin;Antibacterial agent 99;Nafcillin;Antitubercular agent-28;Ochromycinone;Staurosporine;Nucleocidin;(±)-Leucine-13C-1;Ciclopirox-d11;Ciclopirox olamine;Clotrimazole-d5;SQ109;Neomycin sulfate;Bauer-7-ene-3β,16α-diol;Aminothiazole Trending products：Recombinant Proteins | Bioactive Screening Libraries | […]

CC-17369

Posted on December 26, 2022 by haoyuan2014

For research use only. We do not sell to patients. CC-17369 CAS No. : 1547162-46-8 Biological Activity：CC-17369 (7-Hydroxy pomalidomide) is a metabolite of Pomalidomide. CC-17369 is the Pomalidomide -based cereblon (CRBN) ligand used in the recruitment of CRBN protein. CC-17369 can be connected to the ligand for protein by a linker to form PROTAC. Research […]

(S)-(-)-Bay-K-8644

Posted on December 26, 2022 by haoyuan2014

For research use only. We do not sell to patients. (S)-(-)-Bay-K-8644 CAS No. : 98625-26-4 Biological Activity：(S)-(-)-Bay-K-8644 is an agonist of L-type Ca2+ channel. (S)-(-)-Bay-K-8644 activates Ba2+ currents (IBa) (EC50=32 nM). Research Area：Cardiovascular Disease Targets：Calcium Channel Related Screening Libraries:Bioactive Compound Library Plus;Membrane Transporter/Ion Channel Compound Library;Neuronal Signaling Compound Library;Reprogramming Compound Library;Anti-Cardiovascular Disease Compound Library; Related […]

(S)-GNE-140

Posted on December 26, 2022 by haoyuan2014

For research use only. We do not sell to patients. (S)-GNE-140 CAS No. : 2003234-64-6 Biological Activity：(S)-GNE-140 is the less active enantiomer of GNE-140 which can inhibit Lactate dehydrogenase A (LDHA). Research Area：Cancer Targets：Lactate Dehydrogenase Related Screening Libraries:Bioactive Compound Library Plus;Metabolism/Protease Compound Library;Anti-Cancer Compound Library;Glycolysis Compound Library;Anti-Cancer Metabolism Compound Library;Glucose Metabolism Compound Library;Targeted Diversity Library; […]

Acoramidis hydrochloride

Posted on December 26, 2022 by haoyuan2014

For research use only. We do not sell to patients. Acoramidis hydrochloride CAS No. : 2242751-53-5 Biological Activity：Acoramidis (AG10) hydrochloride is an orally active and selective kinetic stabilizer of WT and V122I-TTR (transthyretin). Acoramidis (AG10) hydrochloride is used in the study for transthyretin amyloidosis[2]. Research Area：Endocrinology|Metabolic Disease Targets：Transthyretin (TTR) Related Screening Libraries:Drug Repurposing Compound Library […]

Hydroxy naphthol blue disodium

Posted on December 26, 2022 by haoyuan2014

For research use only. We do not sell to patients. Hydroxy naphthol blue disodium CAS No. : 165660-27-5 Biological Activity：Hydroxy naphthol blue disodium, an azo dye, is a metal indicator for calcium and a colorimetric reagent for alkaline earth metal ions ( λmax = 650 nm). In the pH range between 12 and 13, the […]

EB-0156

Posted on December 26, 2022 by haoyuan2014

For research use only. We do not sell to patients. EB-0156 Biological Activity：EB-0156 is a potent inhibitor of ER α-glucosidases (α-Glu) Iand II with IC50s of 0.0479 and less than 0.001 μM, respectively. EB-0156 is a N-substituted derivative of valiolamine with broad-spectrum antiviral. EB-0156 has the potential for the reseach of broad-spectrum agent against the […]