Year: 2023

For research use only. We do not sell to patients. CHD1Li 6.11 CAS No. : 2716890-91-2 Biological Activity：CHD1Li 6.11 is a potent oncogenic CHD1L inhibitor (IC50=3.3 µM for cat-CHD1L recombinant protein). CHD1Li 6.11 is an orally bioavailable antitumor agent, significantly reducing the tumor volume of CRC xenografts generated from isolated quasi mesenchymal cells (M-phenotype), which […]

For research use only. We do not sell to patients. Perakizumab CAS No. : 89957-37-9 Biological Activity：Perakizumab (RG4934) is a humanized IgG1κ monoclonal antibody against IL-17A (Interleukin Related). Perakizumab can be uesd for the research of autoimmune diseases, such as psoriatic arthritis. Research Area：Inflammation/Immunology Targets：Interleukin Related Related Small Molecules:AX-024;Ginsenoside F3;PNRI-299;CTX-471;Ac-YVAD-CHO;Deucravacitinib;Mulberroside A;NFAT Transcription Factor Regulator-1;IL-17A antagonist […]

For research use only. We do not sell to patients. AZD-2461 CAS No. : 1174043-16-3 Biological Activity：AZD-2461 is a potent PARP inhibitor, with IC50s of 5 nM, 2 nM and 200 nM for PARP1, PARP2 and PARP3, respectively. Research Area：Cancer Targets：PARP Related Screening Libraries:Clinical Compound Library Plus;Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;Epigenetics Compound […]

For research use only. We do not sell to patients. Bauer-7-ene-3β,16α-diol CAS No. : 214351-30-1 Biological Activity：Bauer-7-ene-3β,16α-diol, a triterpenoid, is a natural product that can be isolated from dried flower buds of Tussilago farfara L. or Petasites tricholobus (Compositae). Bauer-7-ene-3β,16α-diol shows medium antibacterial activity against E. coli. Research Area：Infection Targets：Bacterial Related Small Molecules:Sandramycin;LLO (91-99);Gepotidacin;Oritavancin;Azlocillin sodium […]

For research use only. We do not sell to patients. mIDH1-IN-1 CAS No. : 2757155-96-5 Biological Activity：mIDH1-IN-1 (compound 43) is a potent and selective mIDH1 (mutant isocitrate dehydrogenases 1) inhibitor, with an IC50 of 961.5 nM. mIDH1-IN-1 potently inhibits intracellular 2-HG (2-hydroxyglutarate) production in HT1080 cells, with an EC50 of 208.6 ± 8.0 nM. mIDH1-IN-1 […]

For research use only. We do not sell to patients. FXR agonist 4 Biological Activity：FXR agonist 4 (compound 10a) is an agonist of farnesoid X receptor (FXR) with an EC50 value of 1.05 μM. FXR agonist 4 effectively improves hyperlipidemia, hepatic steatosis, insulin resistance and hepatic inflammation in DIO mice. FXR agonist 4 can be […]