NCT-502

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NCT-502

CAS No. : 1542213-00-2

Biological Activity:NCT-502 is a human phosphoglycerate dehydrogenase (PHGDH) inhibitor, cytotoxic to PHGDH-dependent cancer cells, and reduces glucose-derived serine production, with an IC50 of 3.7 μM against PHGDH.

Research Area:Cancer

Targets:Phosphoglycerate Dehydrogenase (PHGDH)

Related Screening Libraries:Bioactive Compound Library Plus;Metabolism/Protease Compound Library;Anti-Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Targeted Diversity Library;

Related Small Molecules:BI-4916;PHGDH-inactive;NCT-503;CBR-5884

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