2023 - epigenetics modulation frontier

Carbostyril 165

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. Carbostyril 165 CAS No. : 26078-23-9 Biological Activity：Carbostyril 165 is an electronically neutral fluorescent dye (Ex: 351/364 nm, Em: >400 nm). Research Area：Others Targets：Others Related Small Molecules:Immune initiator-1;Obiltoxaximab;DIBAC-GGFG-NH2CH2-Dxd;Cyanine5.5 maleimide chloride;Cymarin;Z-Glycine;2-Deoxy-2-fluoro-D-glucose-13C,d7;Water-18O;Fmoc-N-Me-D-Ala-OH;3,5-Diiodo-L-tyrosine;N3-Pen-Dde;Zimeldine-d6;Ornidazole diol;Nylidrin hydrochloride;PFI-653;N-Arachidonoyl Taurine-d4;OVA Peptide (323-339);((3-Fluorophenyl)sulfonyl)glycine;7ß-Hydroxycholesterol-d7;MALAT1-IN-1;Sibiricose A1;Mefruside-d3;Ethacrynic acid mercapturate-d3;FLAG peptide;Neocurdione Trending products：Recombinant Proteins | Bioactive Screening […]

Ginsenoside F3

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. Ginsenoside F3 CAS No. : 62025-50-7 Biological Activity：Ginsenoside F3, a component of PPTGs (an minor saponin in the leaves of Panax ginseng), has immunoenhancing activity by regulating production and gene expression of type 1 cytokines (IL-2, IFN-gamma) and type 2 cytokines (IL-4 and IL-10). Research […]

Nuciferine

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. Nuciferine CAS No. : 475-83-2 Biological Activity：Nuciferine is an antagonist at 5-HT2A (IC50=478 nM), 5-HT2C (IC50=131 nM), and 5-HT2B (IC50=1 μM), an inverse agonist at 5-HT7 (IC50=150 nM), a partial agonist at D2 (EC50=64 nM), D5 (EC50=2.6 μM) and 5-HT6 (EC50=700 nM), an agonist at […]

PAMP-12

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. PAMP-12 CAS No. : 929905-12-4 Biological Activity：PAMP-12 is a potent MRGPRX2 (MrgX2) agonist (EC50=20-50 nM). PAMP-12 is an endogenous peptide that elicit hypotension through inhibiting catecholamine secretion from sympathetic nerve endings and adrenal chromaffin cells. Research Area：Cardiovascular Disease Targets：Others Related Small Molecules:Immune initiator-1;Obiltoxaximab;DIBAC-GGFG-NH2CH2-Dxd;Cyanine5.5 maleimide chloride;Cymarin;Z-Glycine;2-Deoxy-2-fluoro-D-glucose-13C,d7;Water-18O;Fmoc-N-Me-D-Ala-OH;3,5-Diiodo-L-tyrosine;N3-Pen-Dde;Zimeldine-d6;Ornidazole […]

Yohimbine

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. Yohimbine CAS No. : 146-48-5 Biological Activity：Yohimbine is a potent and relatively nonselective alpha 2-adrenergic receptor (AR) antagonist, with IC50 of 0.6 μM. IC50 value: 0.6 uM [1] Target: alpha 2-adrenergic receptor in vitro: Yohimbine inhibits alpha2-receptor antagonist with Ki of 1.05 nM, 1.19 nM, […]

Lenalidomide hydrochloride

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. Lenalidomide hydrochloride CAS No. : 1243329-97-6 Biological Activity：Lenalidomide hydrochloride (CC-5013 hydrochloride), a derivative of Thalidomide, acts as molecular glue. Lenalidomide hydrochloride is an orally active immunomodulator. Lenalidomide hydrochloride (CC-5013 hydrochloride) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and […]

NS5A-IN-1

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. NS5A-IN-1 Biological Activity：NS5A-IN-1 is a prodrug of the HCV NS5A inhibitor Pibrentasvir (ABT-530). Research Area：Infection Targets：HCV Protease Related Small Molecules:Grazoprevir potassium salt;BMS-986144;Ciluprevir;Faldaprevir-d6;Isoeuphorbetin;NS5A-IN-4;Coblopasvir;Glecaprevir;NS5A-IN-3;HCVP-IN-1;Paritaprevir dihydrate;Clemizole hydrochloride;BI-1230;AZD-7295;Faldaprevir;IDX184;HZ-1157;GSK2818713;Narlaprevir;AL-611 Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides About […]

PROTAC VEGFR-2 degrader-2

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. PROTAC VEGFR-2 degrader-2 CAS No. : 2353417-85-1 Biological Activity：PROTAC VEGFR-2 degrader-2（PROTAC-4）, a PROTAC VEGFR-2 degrader, exhibits little VEGFR-2 inhibition (IC50> 1 μM) and anti-proliferative activity against EA.hy926 cells (IC50> 100μM). Research Area：Cancer Targets：VEGFR|PROTACs Related Small Molecules:(Z)-FeCP-oxindole;PROTAC Sirt2 Degrader-1;DB0614;VEGFR-2-IN-24;BMS-690514;dTAGV-1-NEG;CCT367766 formic;Henatinib;PI3K/VEGFR2-IN-1;HDAC6 degrader-1;PROTAC Axl Degrader 2;PhosTAC7;MS98;JPS014;PROTAC PARP1 degrader;MD-224;Hydroxytanshinone […]

2-Iodoaniline

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. 2-Iodoaniline CAS No. : 615-43-0 Biological Activity：2-Iodoaniline (2-Iodophenylamine) is an aniline derivative, and has potential hepatotoxic and nephrotoxic activity. Research Area：Others Targets：Others Related Screening Libraries:Fragment Library; Related Small Molecules:Immune initiator-1;Obiltoxaximab;DIBAC-GGFG-NH2CH2-Dxd;Cyanine5.5 maleimide chloride;Cymarin;Z-Glycine;2-Deoxy-2-fluoro-D-glucose-13C,d7;Water-18O;Fmoc-N-Me-D-Ala-OH;3,5-Diiodo-L-tyrosine;N3-Pen-Dde;Zimeldine-d6;Ornidazole diol;Nylidrin hydrochloride;PFI-653;N-Arachidonoyl Taurine-d4;OVA Peptide (323-339);((3-Fluorophenyl)sulfonyl)glycine;7ß-Hydroxycholesterol-d7;MALAT1-IN-1;Sibiricose A1;Mefruside-d3;Ethacrynic acid mercapturate-d3;FLAG peptide;Neocurdione Trending products：Recombinant Proteins | […]

Curcumin

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. Curcumin CAS No. : 458-37-7 Biological Activity：Curcumin (Diferuloylmethane), a natural phenolic compound, is a p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription. Curcumin shows inhibitory effects on NF-κB and MAPKs, and has diverse pharmacologic effects including anti-inflammatory, […]