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CAS No. : 458-37-7

Biological Activity:Curcumin (Diferuloylmethane), a natural phenolic compound, is a p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription. Curcumin shows inhibitory effects on NF-κB and MAPKs, and has diverse pharmacologic effects including anti-inflammatory, antioxidant, antiproliferative and antiangiogenic activities. Curcumin induces stabilization of Nrf2 protein through Keap1 cysteine modification.

Research Area:Cancer

Targets:Epigenetic Reader Domain|Ferroptosis|Autophagy|Keap1-Nrf2|Influenza Virus|Mitophagy|Histone Acetyltransferase

Related Screening Libraries:Natural Product Library Plus;Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Anti-Infection Compound Library;Apoptosis Compound Library;Epigenetics Compound Library;Immunology/Inflammation Compound Library;NF-κB Signaling Compound Library;Stem Cell Signaling Compound Library;Natural Product Library;Histone Modification Research Compound Library;Anti-Cancer Compound Library;Clinical Compound Library;Antiviral Compound Library;Autophagy Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Antioxidant Compound Library;Reprogramming Compound Library;Anti-diabetic Compound Library;Oxygen Sensing Compound Library;Ferroptosis Compound Library;Anti-COVID-19 Compound Library;Medicine Food Homology Compound Library;Phenols Library;Traditional Chinese Medicine Active Compound Library;FDA Approved & Pharmacopeial Drug Library;Drug-Induced Liver Injury (DILI) Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Blood Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Anti-Obesity Compound Library;Mitochondria-Targeted Compound Library;Transcription Factor-Targeted Library;Food-Sourced Compound Library ;Rare Diseases Drug Library;Children’s Drug Library;Anti-Cancer Natural Product Library;Antiviral Traditional Chinese Medicine Active Compound Library;Anti-inflammatory Traditional Chinese Medicine Active Compound Library;Plant-Sourced Natural Product Library;Human Metabolite Library;Anti-Prostate Cancer Compound Library;Anti-Pulmonary Fibrosis Compound Library;Non-steroidal Anti-Inflammatory Compound Library;Anti-Aging Natural Product Library;

Related Small Molecules:CIL56;DB0614;RVX-297;BRD4 Inhibitor-19;UNC6349 (Ket2);Ciclopirox-d11;Mangiferin;Antioxidant agent-5;Ciclopirox olamine;(R)-Camptothecin-d5;GSK6853;GSK4028;CBP/p300-IN-19 hydrochloride;Glaucine;Melatonin-d3;Hypericin;Neuraminidase-IN-3;NSC 694621;SR-0813;Antroquinonol;Inobrodib;PCAF-IN-2;FGI-106 tetrahydrochloride;Molnupiravir;Apabetalone;Onradivir

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