For research use only. We do not sell to patients.
CAS No. : 475-83-2
Biological Activity：Nuciferine is an antagonist at 5-HT2A (IC50=478 nM), 5-HT2C (IC50=131 nM), and 5-HT2B (IC50=1 μM), an inverse agonist at 5-HT7 (IC50=150 nM), a partial agonist at D2 (EC50=64 nM), D5 (EC50=2.6 μM) and 5-HT6 (EC50=700 nM), an agonist at 5-HT1A (EC50=3.2 μM) and D4 (EC50=2 μM) receptor.
Research Area：Neurological Disease
Targets：Dopamine Receptor|5-HT Receptor
Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Neuronal Signaling Compound Library;Natural Product Library;Medicine Food Homology Compound Library;Neurotransmitter Receptor Compound Library;Traditional Chinese Medicine Active Compound Library; FDA Approved & Pharmacopeial Drug Library;Anti-Alzheimer’s Disease Compound Library;Alkaloids Library;Anti-Parkinson’s Disease Compound Library;Antidepressant Compound Library;Plant-Sourced Natural Product Library;5-HT Receptor Compound Library;Coagulation and Anti-coagulation Compound Library;
Related Small Molecules:F 13714;Alizapride hydrochloride;Thioproperazine;Mosapride-d5;Bromopride-d3;Glaucine;Renzapride;SB-277011 dihydrochloride;LY 344864 racemate;Harmine hydrochloride;MIF-1 TFA;Valerenic acid;Arotinolol;Sulpiride;(Rac)-Razpipadon;Melitracen-d6 hydrochloride;Clebopride malate;WAY-100635;Nelotanserin;Flupentixol-d4 dihydrochloride
- MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use；
- Structurally and synthetically diverse biologically active compounds；
- roduct quality is the key to our success and we take pride in offering only the highest-grade products.；
- We provide HNMR, LC-MS, HPLC, stability testing and activity assays of our products to clients.；
- Product identity, quality, purity and activity are assured by our robust quality control programs and procedures.；
- Customized order volume ranging from milligrams to kilograms scale；
Structurally and synthetically diverse biologically active compounds；
We provide customer-oriented services. To explore more, please contact us at [email protected]. Our team will gladly assist you.