Tag: inhibitor

For research use only. We do not sell to patients. Perphenazine-d8 dihydrochloride Biological Activity：Perphenazine D8 Dihydrochloride is the deuterium labeled Perphenazine, which is a typical antipsychotic drug(5-HT, Dopamine receptor ligand). Research Area：Endocrinology|Neurological Disease Targets：Dopamine Receptor|Adrenergic Receptor|5-HT Receptor|Histamine Receptor Related Small Molecules:F 13714;Alizapride hydrochloride;Thioproperazine;Mosapride-d5;Todralazine;Bromopride-d3;ARC 239 dihydrochloride;Nuciferine;Yohimbine;Tripelennamine;Glaucine;Salbutamol;Renzapride;SB-277011 dihydrochloride;Brompheniramine-d6 maleate;BI-167107;LY 344864 racemate;Samelisant;Harmine hydrochloride Trending products：Recombinant Proteins  |  Bioactive […]

For research use only. We do not sell to patients. AZ-3 CAS No. : 2228908-91-4 Biological Activity：AZ-3 is a potent and selective JAK1 inhibitor with an IC50 of 34 nM. Research Area：Cancer Targets：JAK Related Small Molecules:JAK3/BTK-IN-1;AT9283;Benzene hexabromide;(E/Z)-Zotiraciclib;JAK-IN-10;Baricitinib-d3;JAK3-IN-6;Coumermycin A1;Deucravacitinib;Momelotinib-3,3,5,5-d4;SJ10542;Delgocitinib;Upadacitinib;α7 nAchR-JAK2-STAT3 agonist 1;Filgotinib-d4;AZD-1480;JAK-IN-20;JAK3 covalent inhibitor-1;JAK3-IN-12;(R)-Reticuline-d3;JAK-IN-23;TCJL37;JAK-IN-5;NSC 42834 Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  |  […]

For research use only. We do not sell to patients. (Z)-FeCP-oxindole CAS No. : 1137967-28-2 Biological Activity：(Z)-FeCP-oxindole is a selective human vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with an IC50 value of 200 nM. (Z)-FeCP-oxindole can significantly inhibit VEGFR1 and PDGFRa or b at 10 μM. (Z)-FeCP-oxindole has some anticancer activity, acting on […]

For research use only. We do not sell to patients. (E/Z)-HA155 CAS No. : 1229652-22-5 Biological Activity：(E/Z)-HA155 is a potent autotaxin (ATX) type I inhibitor. (E/Z)-HA155 can be used for researching cancer, fibrotic diseases, inflammation, pain and angiogenesis. Research Area：Cancer|Inflammation/Immunology|Neurological Disease Targets：Phosphodiesterase (PDE) Related Small Molecules:Senazodan hydrochloride;Enpp/Carbonic anhydrase-IN-1;ATX inhibitor 22;Carbazeran citrate;Bay 60-7550;BC11-38;Deltarasin hydrochloride;Glaucine;Ziritaxestat;Udenafil-d7;D159687;ITI-214;PDE10-IN-5;ICI 153110;Furamidine dihydrochloride;ML-030;PDE4-IN-10;Mirodenafil-d7 […]

For research use only. We do not sell to patients. Sandramycin CAS No. : 100940-65-6 Biological Activity：Sandramycin ia a cyclic depsipeptide antibiotic isolated from cultured broth of a Nocardioides sp. Sandramycin is also a DNA intercalator that potently binds DNA and is an ADC cytotoxin. Sandramycin is active against Gram-positive bacteria and has potent antitumor […]

For research use only. We do not sell to patients. RORγt inhibitor 1 CAS No. : 1561770-72-6 Biological Activity：RORγt inhibitor 1 is a RORγt allosteric inhibitor with an IC50 value of 1 nM. Research Area：Inflammation/Immunology Targets：ROR Related Small Molecules:GNE-6468;SR3335;RORγt inverse agonist 30;GNE-0946;RORγt inverse agonist 13;Vimirogant hydrochloride;SR2211;Bevurogant;ROR agonist-1;RORγt Inverse agonist 8;CD12681;S18-000003;RORγt inhibitor 2;XY018;RORγt inverse agonist 29;SR1001;Cedirogant;SHR168442;ARN-6039;A-9758;Cintirorgon;Nobiletin;TAK-828F;RORγt […]

For research use only. We do not sell to patients. PFI-653 CAS No. : 2173134-00-2 Biological Activity：PFI-653 (Vanin-1-IN-1) is an inhibitor of vanin-1 enzyme which is a cell surface associated, giycosyiphosphatidyS inositol (GPi) anchored protein and plays an important role in metabolism and inflammation. Research Area：Metabolic Disease|Inflammation/Immunology Targets：Others Related Screening Libraries:Covalent Screening Library Plus; Bioactive […]

For research use only. We do not sell to patients. PROTAC Sirt2 Degrader-1 CAS No. : 2098487-75-1 Biological Activity：PROTAC Sirt2 Degrader-1 is a SirReal-based PROTAC, acts as a Sirt2 degrader, composed of a highly potent and isotype-selective Sirt2 inhibitor, a linker, and a bona fide Cereblon ligand for E3 ubiquitin ligase. PROTAC Sirt2 Degrader-1 shows […]

For research use only. We do not sell to patients. Akt/NF-κB/JNK-IN-1 Biological Activity：Akt/NF-κB/JNK-IN-1 (Compound 2i) is an inhibitor of Akt, NF-κB and JNK signaling pathways. Akt/NF-κB/JNK-IN-1 inhibits nitric oxide production with an IC50 of 3.15 μM. Akt/NF-κB/JNK-IN-1 shows anti-inflammatory activities. Research Area：Inflammation/Immunology Targets：Akt|TNF Receptor|NF-κB|JNK|COX Related Small Molecules:COX-2/5-LOX-IN-3;JNK3 inhibitor-2;AX-024;Icariside F2;IKKγ NBD Inhibitory Peptide TFA;Mangiferin;Antioxidant agent-5;Cyclovirobuxine D;ALPK1-IN-1;Regaloside […]

For research use only. We do not sell to patients. SJB2-043 CAS No. : 63388-44-3 Biological Activity：SJB2-043 is an inhibitor of the native USP1/UAF1 complex with IC50 of 544 nM. Research Area：Cancer Targets：Deubiquitinase Related Screening Libraries:Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;Anti-Cancer Compound Library;Anti-Aging Compound Library;Ubiquitination Compound Library;Targeted Diversity Library; Related Small Molecules:SJB3-019A;USP7-IN-1;DUB-IN-2;6RK73;IU1-248;HBX 41108;BC-1471;P005091;USP5-IN-1;b-AP15;STAMBP-IN-1;FT827;(R)-FT671;USP7-IN-9;FT709;USP7-IN-3;LCAHA;USP8-IN-1;USP1-IN-2;8RK64;TCID;FT3967385;LDN-57444;RA-9;LDN-91946;HBX […]