Tag: Antagonist|Inhibitor

For research use only. We do not sell to patients. AMD 3465 CAS No. : 185991-24-6 Biological Activity：AMD 3465 (GENZ-644494) is a potent antagonist of CXCR4, inhibits binding of 12G5 mAb and CXCL12AF647 to CXCR4, with IC50s of 0.75 nM and 18 nM in SupT1 cells; AMD 3465 also potently inhibits the replication of X4 […]

For research use only. We do not sell to patients. MK-571 sodium CAS No. : 115103-85-0 Biological Activity：MK-571 (L-660711) sodium is an orally active, potent and selective competitive leukotriene D4 (LTD4) receptor antagonist, with Ki values of 0.22 and 2.1 nM in guinea pig and human lung membranes, respectively. MK-571 sodium is also a inhibitor […]

For research use only. We do not sell to patients. Asenapine-d3 CAS No. : 1180843-72-4 Biological Activity：Asenapine-d3 (Org 5222-d3) is the deuterium labeled Asenapine. Asenapine (Org 5222), an atypical antipsychotic, is an antagonist of serotonin receptors (pKi: 8.4-10.5), adrenoceptors (pKi: 8.9-9.5), dopamine receptors (pKi: 8.9-9.4) and histamine receptors (pKi: 8.2-9.0). Asenapine can be used in […]

For research use only. We do not sell to patients. Bopindolol fumarate CAS No. : 79125-22-7 Biological Activity：Bopindolol ((±)-Bopindolol) fumarate is an orally active antagonist of β-adrenoceptors (ARs) with partial agonist activity. Bopindolol fumarate is non-selective for β1- and β2-ARs and has low affinity for β3-AR subtype. Bopindolol fumarate has intrinsic sympathomimetic as well as […]

For research use only. We do not sell to patients. IT1t CAS No. : 864677-55-4 Biological Activity：IT1t is a potent CXCR4 antagonist; inhibits CXCL12/CXCR4 interaction with an IC50 of 2.1 nM. Research Area：Inflammation/Immunology|Endocrinology Targets：CXCR|HIV Related Small Molecules:Nicotinamide N-oxide;HIV-1 TAT (48-60);Seletracetam lithium;HIV-IN-2;Triptonine B;FC131;Peritassine A;CXCR4 antagonist 2;Flavopiridol;AMG 487 (S-enantiomer);TAT (48-57);FGI-106 tetrahydrochloride;(Z)-9-Propenyladenine;Apabetalone;CXCR4 antagonist 6;Decanoyl-RVKR-CMK TFA;ONX-0914 TFA;Apelin-36(rat, mouse);Ulonivirine Trending […]

For research use only. We do not sell to patients. Brompheniramine CAS No. : 86-22-6 Biological Activity：Brompheniramine ((±)-Brompheniramine) is a potent and orally active antihistamine of the alkylamine class. Brompheniramine is a selective histamine H1 receptor antagonist with a Kd of 6.06 nM. Brompheniramine can block the hERG channels, calcium channels, and sodium channels with […]