MK-571 sodium

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MK-571 sodium

CAS No. : 115103-85-0

Biological Activity:MK-571 (L-660711) sodium is an orally active, potent and selective competitive leukotriene D4 (LTD4) receptor antagonist, with Ki values of 0.22 and 2.1 nM in guinea pig and human lung membranes, respectively. MK-571 sodium is also a inhibitor of multidrug resistance-associated protein MRP4 (ABCC4) and ABCC1 (MRP1). MK-571 sodium inhibits constitutive and antigen-stimulated S1P (sphingosine-1-phosphate) release[2][3].

Research Area:Inflammation/Immunology

Targets:Leukotriene Receptor|LPL Receptor

Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Immunology/Inflammation Compound Library;Orally Active Compound Library;Anti-Pulmonary Fibrosis Compound Library;Cancer Stem Cells Compound Library;

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