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CAS No. : 86-22-6
Biological Activity：Brompheniramine ((±)-Brompheniramine) is a potent and orally active antihistamine of the alkylamine class. Brompheniramine is a selective histamine H1 receptor antagonist with a Kd of 6.06 nM. Brompheniramine can block the hERG channels, calcium channels, and sodium channels with IC50s of 0.90 μM, 16.12 μM and 21.26 μM, respectively. Brompheniramine has anticholinergic, antidepressant and anesthetic properties and can be used for allergic rhinitis research.
Research Area：Endocrinology|Inflammation/Immunology|Neurological Disease
Targets：Calcium Channel|mAChR|Histamine Receptor|Sodium Channel|Potassium Channel
Related Small Molecules:VU0357017 hydrochloride;Benidipine hydrochloride;Lu AE98134;CaV1.3 antagonist-1;14-Deoxyandrographolide;TBPB;Kv3 modulator 2;Imidafenacin;Zandatrigine;Sabcomeline;(Rac)-MEM 1003;Tripelennamine;Glaucine;Veratridine;MK-6884;Efonidipine hydrochloride monoethanolate;L-Ascorbic acid sodium salt;Brompheniramine-d6 maleate;Pinacidil;MRS 1523;GX-674
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