2023 - epigenetics modulation frontier

UNC6349 (Ket2)

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. UNC6349 (Ket2) Biological Activity：UNC6349 (Ket2), a diethyllysine (Ket2)-containing ligand, binds to wild-type CBX5, with a KD of 3.2 μM. Research Area：Cancer Targets：Epigenetic Reader Domain Related Small Molecules:RVX-297;BRD4 Inhibitor-19;Curcumin;GSK6853;GSK4028;SR-0813;Inobrodib;Apabetalone;OF-1;I-CBP112;A-485;PLX51107;FKBP12 PROTAC dTAG-7;I-BET151;GSK040;BRM/BRG1 ATP Inhibitor-4;PBRM1-BD2-IN-5;MI-136;IACS-9571;SF2523;L-Moses dihydrochloride;KB02-JQ1;GSK620;INCB-057643;Bromodomain IN-1;QCA570;BRM/BRG1 ATP Inhibitor-1;Ziftomenib Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural […]

Talnetant hydrochloride

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. Talnetant hydrochloride CAS No. : 204519-66-4 Biological Activity：Talnetant (SB 223412) hydrochloride is a selective, competitive, brain-permeable NK3 receptor antagonist with a Ki of 1.4 nM in hNK-3-CHO cells. Talnetant hydrochloride is 100-fold more selective for hNK-3 relative to the hNK-2 receptor and has no affinity […]

BI-3812

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. BI-3812 CAS No. : 2166387-64-8 Biological Activity：BI-3812 is potent and efficacious BCL6 inhibitor, inhibiting the BTB domain of BCL6, with an IC50 of ≤3 nM; BI-3812 has antitumor activity. Research Area：Cancer Targets：Bcl-2 Family Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;Anti-Cancer Compound Library;Chemical Probe Library;Anti-Blood […]

CYPMPO

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. CYPMPO CAS No. : 934182-09-9 Biological Activity：CYPMPO is a spin-trapping reagent. CYPMPO, a cyclic DEPMPO-type nitrone, is evaluated for spin-trapping capabilities toward hydroxyl and superoxide radicals. anti-oxidant and anti-tumor activity. Research Area：Cancer Targets：Reactive Oxygen Species Related Small Molecules:D-α-Hydroxyglutaric acid disodium;Chitoheptaose heptahydrochloride;N-Acetyl-D-cysteine;Topoisomerase I/II inhibitor 3;Antioxidant agent-5;ROS-ERS inducer […]

(±)-Leucine-13C-1

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. (±)-Leucine-13C-1 CAS No. : 82152-65-6 Biological Activity：(±)-Leucine-13C-1 (DL-Leucine-13C-1) is the 13C-labeled (±)-Leucine. (±)-Leucine (DL-Leucine), an isomer of Leucine, chemosterilant and dietary additive. (±)-Leucine inhibits growth of Escherichia coli HfrH by 92.08%. Research Area：Metabolic Disease Targets：Bacterial|Endogenous Metabolite Related Small Molecules:D-α-Hydroxyglutaric acid disodium;Nicotinamide N-oxide;3-Hydroxyglutaric acid-d5;DPPC-d62;SDMA-d6;2-Mercaptobenzothiazole;Sandramycin;LLO (91-99);N-Acetyl-L-glutamic acid-d5;Gepotidacin;(3R,5S)-3-Hydroxy […]

1,2-Distearoyl-sn-glycerol

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. 1,2-Distearoyl-sn-glycerol CAS No. : 10567-21-2 Biological Activity：1,2-Distearoyl-sn-glycerol (DSG; 1,2-Dioctadecanoyl-sn-glycerol) acts as an internal standard for Separation and identification of molecular species of 1,2-diacyl-sn-glycerol (DAG). Research Area：Others Targets：Others Related Small Molecules:Immune initiator-1;Obiltoxaximab;DIBAC-GGFG-NH2CH2-Dxd;Cyanine5.5 maleimide chloride;Cymarin;Z-Glycine;2-Deoxy-2-fluoro-D-glucose-13C,d7;Water-18O;Fmoc-N-Me-D-Ala-OH;3,5-Diiodo-L-tyrosine;N3-Pen-Dde;Zimeldine-d6;Ornidazole diol;Nylidrin hydrochloride;PFI-653;N-Arachidonoyl Taurine-d4;OVA Peptide (323-339);((3-Fluorophenyl)sulfonyl)glycine;7ß-Hydroxycholesterol-d7;MALAT1-IN-1;Sibiricose A1;Mefruside-d3;Ethacrynic acid mercapturate-d3;FLAG peptide;Neocurdione Trending products：Recombinant Proteins […]

Xevinapant

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. Xevinapant CAS No. : 1071992-99-8 Biological Activity：Xevinapant (AT-406) is a potent and orally bioavailable Smac mimetic and an antagonist of IAPs, and it binds to XIAP, cIAP1, and cIAP2 proteins with Ki of 66.4, 1.9, and 5.1 nM, respectively. Research Area：Cancer Targets：IAP|Apoptosis Related Screening Libraries:Drug […]

3′-Hydroxy Repaglinide-d5

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. 3′-Hydroxy Repaglinide-d5 CAS No. : 1352792-15-4 Biological Activity：3′-Hydroxy Repaglinide D5 is the deuterium labeled 3′-Hydroxy Repaglinide. 3′-Hydroxy Repaglinide is a main CYP2C8 metabolite of Repaglinide. Research Area：Metabolic Disease Targets：Drug Metabolite Related Small Molecules:Nicotinamide N-oxide;4-Hydroxyphenylbutazone;Ampyrone;Resveratrol-3-O-sulfate sodium;Sonidegib metabolite M48;Isonicotinic acid;Cycloguanil hydrochloride;Hydroxytanshinone IIA;Endoxifen;Fodipir;Regorafénib N-oxyde (M2)-13C,d3;AZ7550 Mesylate;AR-13324 M1 metabolite;Thyroxine […]

Tilavonemab

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. Tilavonemab CAS No. : 2096513-89-0 Biological Activity：Tilavonemab (ABBV-8E12) is a humanised anti-tau antibody that binds amino acids 25-30 near the N-terminal end of the tau protein. Tilavonemab blocks the ability of human and mouse neurons to take up tau aggregates and reduces brain atrophy. Tilavonemab […]

Benzene hexabromide

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. Benzene hexabromide CAS No. : 1837-91-8 Biological Activity：Benzene hexabromide, a bromohydrocarbon, is a potent inhibitor of JAK2 tyrosine kinase autophosphorylation. Research Area：Cancer Targets：JAK Related Small Molecules:AZ-3;JAK3/BTK-IN-1;AT9283;(E/Z)-Zotiraciclib;JAK-IN-10;Baricitinib-d3;JAK3-IN-6;Coumermycin A1;Deucravacitinib;Momelotinib-3,3,5,5-d4;SJ10542;Delgocitinib;Upadacitinib;α7 nAchR-JAK2-STAT3 agonist 1;Filgotinib-d4;AZD-1480;JAK-IN-20;JAK3 covalent inhibitor-1;JAK3-IN-12;(R)-Reticuline-d3;JAK-IN-23;TCJL37;JAK-IN-5;NSC 42834 Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent […]