2023 - epigenetics modulation frontier

Esmolol Acid-d7

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. Esmolol Acid-d7 CAS No. : 1346598-79-5 Biological Activity：Esmolol Acid-d7 is the deuterium labeled Esmolol Acid. Research Area：Others Targets：Others Related Small Molecules:Immune initiator-1;Obiltoxaximab;DIBAC-GGFG-NH2CH2-Dxd;Cyanine5.5 maleimide chloride;Cymarin;Z-Glycine;2-Deoxy-2-fluoro-D-glucose-13C,d7;Water-18O;Fmoc-N-Me-D-Ala-OH;3,5-Diiodo-L-tyrosine;N3-Pen-Dde;Zimeldine-d6;Ornidazole diol;Nylidrin hydrochloride;PFI-653;N-Arachidonoyl Taurine-d4;OVA Peptide (323-339);((3-Fluorophenyl)sulfonyl)glycine;7ß-Hydroxycholesterol-d7;MALAT1-IN-1;Sibiricose A1;Mefruside-d3;Ethacrynic acid mercapturate-d3;FLAG peptide;Neocurdione Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent […]

Coumarin hydrazine

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. Coumarin hydrazine CAS No. : 113707-87-2 Biological Activity：Coumarin hydrazine is a fluorescent chemical probe (λex=420–450/λem=468 nm) to label cellular protein- and lipid-bound carbonyls. Research Area：Others Targets：Others Related Small Molecules:Immune initiator-1;Obiltoxaximab;DIBAC-GGFG-NH2CH2-Dxd;Cyanine5.5 maleimide chloride;Cymarin;Z-Glycine;2-Deoxy-2-fluoro-D-glucose-13C,d7;Water-18O;Fmoc-N-Me-D-Ala-OH;3,5-Diiodo-L-tyrosine;N3-Pen-Dde;Zimeldine-d6;Ornidazole diol;Nylidrin hydrochloride;PFI-653;N-Arachidonoyl Taurine-d4;OVA Peptide (323-339);((3-Fluorophenyl)sulfonyl)glycine;7ß-Hydroxycholesterol-d7;MALAT1-IN-1;Sibiricose A1;Mefruside-d3;Ethacrynic acid mercapturate-d3;FLAG peptide;Neocurdione Trending products：Recombinant Proteins | Bioactive […]

Metopimazine Acid-d6

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. Metopimazine Acid-d6 CAS No. : 1215326-10-5 Biological Activity：Metopimazine Acid-d6 is the deuterium labeled Metopimazine Acid. Research Area：Others Targets：Others Related Small Molecules:Immune initiator-1;Obiltoxaximab;DIBAC-GGFG-NH2CH2-Dxd;Cyanine5.5 maleimide chloride;Cymarin;Z-Glycine;2-Deoxy-2-fluoro-D-glucose-13C,d7;Water-18O;Fmoc-N-Me-D-Ala-OH;3,5-Diiodo-L-tyrosine;N3-Pen-Dde;Zimeldine-d6;Ornidazole diol;Nylidrin hydrochloride;PFI-653;N-Arachidonoyl Taurine-d4;OVA Peptide (323-339);((3-Fluorophenyl)sulfonyl)glycine;7ß-Hydroxycholesterol-d7;MALAT1-IN-1;Sibiricose A1;Mefruside-d3;Ethacrynic acid mercapturate-d3;FLAG peptide;Neocurdione Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent […]

Ametantrone

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. Ametantrone CAS No. : 64862-96-0 Biological Activity：Ametantrone (NSC 196473) is an antitumor agent that intercalates into DNA and induces topoisomerase II (TOP2)-mediated DNA break. Research Area：Cancer Targets：DNA/RNA Synthesis Related Small Molecules:ddCTP trisodium;7-TFA-ap-7-Deaza-dA;P1788;Thymidine-13C5,15N;NSC 617145;116-9e;DNA Gyrase-IN-5;DMT-2′-F-Bz-dA;6-Thio-2′-Deoxyguanosine;Antitumor agent-74;Risdiplam;TH287 hydrochloride;Direct Black 38;7-TFA-ap-7-Deaza-ddA;BCH001;NKP-1339;Fialuridine;2′-O-MOE-5-Me-rC;PTC299;2′-F-Bz-dC Phosphoramidite Trending products：Recombinant Proteins | Bioactive Screening […]

BRD4 Inhibitor-19

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. BRD4 Inhibitor-19 CAS No. : 2757865-63-5 Biological Activity：BRD4 Inhibitor-19 is a BET inhibitor with an IC50 of 55 nM for BRD4-BD1. BRD4 Inhibitor-19 can be used for multiple myeloma research. Research Area：Cancer Targets：Epigenetic Reader Domain Related Small Molecules:RVX-297;UNC6349 (Ket2);Curcumin;GSK6853;GSK4028;SR-0813;Inobrodib;Apabetalone;OF-1;I-CBP112;A-485;PLX51107;FKBP12 PROTAC dTAG-7;I-BET151;GSK040;BRM/BRG1 ATP Inhibitor-4;PBRM1-BD2-IN-5;MI-136;IACS-9571;SF2523;L-Moses dihydrochloride;KB02-JQ1;GSK620;INCB-057643;Bromodomain IN-1;QCA570;BRM/BRG1 ATP Inhibitor-1;Ziftomenib Trending products：Recombinant […]

Isouvaretin

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. Isouvaretin Biological Activity：A mixture of uvaretin (HY-N10129) and isouvaretin exhibits significant antibacterial activity against B. subtilis (EC50 8.7 μM) and S. epidermidis (IC50 7.9 μM). Research Area：Infection Targets：Bacterial Related Small Molecules:Sandramycin;LLO (91-99);Gepotidacin;Oritavancin;Azlocillin sodium salt;Herbimycin A;Antibacterial agent 45;Leucomycin;Antibacterial agent 99;Nafcillin;Antitubercular agent-28;Ochromycinone;Staurosporine;Nucleocidin;(±)-Leucine-13C-1;Ciclopirox-d11;Ciclopirox olamine;Clotrimazole-d5;SQ109;Neomycin sulfate;Bauer-7-ene-3β,16α-diol;Aminothiazole Trending products：Recombinant Proteins […]

Boc-Pip-alkyne-Ph-COOH

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. Boc-Pip-alkyne-Ph-COOH Biological Activity：Boc-Pip-alkyne-Ph-COOH is a PROTAC linker, which refers to the alkyl/ether composition. Boc-Pip-alkyne-Ph-COOH can be used in the synthesis of a series of PROTACs, such as ARD-266 (HY-133020). ARD-266 effectively induces degradation of androgen receptor (AR) protein in AR-positive LNCaP, VCaP, and 22Rv1 prostate […]

25-Hydroxycholesterol-d6

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. 25-Hydroxycholesterol-d6 CAS No. : 88247-69-2 Biological Activity：25-Hydroxycholesterol-d6 is the deuterium labeled 25-Hydroxycholesterol. 25-Hydroxycholesterol is a metabolite of cholesterol that is produced and secreted by macrophages in response to Toll-like receptor (TLR) activation. 25-hydroxycholesterol is a potent (EC50≈65 nM) and selective suppressor of IgA production by […]

CaV1.3 antagonist-1

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. CaV1.3 antagonist-1 CAS No. : 1391385-57-1 Biological Activity：CaV1.3 antagonist-1 is a potent and highly selective CaV1.3 L-type calcium channel (LTCC) antagonist with an IC50 of 1.7 μM. CaV1.3 antagonist-1 inhibits CaV1.3 LTCC >600-fold more potently than CaV1.2 LTCC. CaV1.3 antagonist-1, a cyclopentyl derivative, has the […]

14-Deoxyandrographolide

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. 14-Deoxyandrographolide CAS No. : 4176-97-0 Biological Activity：14-Deoxyandrographolide is a labdane diterpene with calcium channel blocking activity. 14-Deoxyandrographolide desensitizes hepatocytes to TNF-α-mediated apoptosis through the release of TNFRSF1A release[2]. Research Area：Metabolic Disease|Neurological Disease Targets：Calcium Channel Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus;Membrane Transporter/Ion Channel […]