Tag: p53 Inhibitor

For research use only. We do not sell to patients. Pifithrin-β CAS No. : 60477-34-1 Biological Activity：Pifithrin-β (PFT β) is a potent p53 inhibitor with an IC50 of 23 μM. Research Area：Cancer Targets：MDM-2/p53 Related Small Molecules:MDM2-p53-IN-15;MC-VC-PABC-SP 141;p53 and MDM2 proteins-interaction-inhibitor (racemic);Navtemadlin;MD-224;Mutant p53 modulator-1;MDM2/4-p53-IN-2;MX69;p-nitro-Pifithrin-α;RG7112;MMRi62;Anticancer agent 50;NSC59984;Pifithrin-β hydrobromide;Ivaltinostat formic;GEM-5;Tenovin-6;PK11007;AM-8735;GN25;RO-5963;PhiKan 083;C16-Ceramide;Pifithrin-α hydrobromide;MA242;Anticancer agent 65;CBL0137 hydrochloride;HDAC-IN-34 Trending products：Recombinant Proteins  […]

For research use only. We do not sell to patients. MS7972 CAS No. : 352553-42-5 Biological Activity：MS7972 is a small molecule that blocks human p53 and CREB binding protein association. MS7972 can almost completely block this BRD interaction at 50 μM. Research Area：Cancer Targets：MDM-2/p53 Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library; Anti-Cancer Compound Library;Autophagy […]

For research use only. We do not sell to patients. Teprasiran CAS No. : 1231737-88-4 Biological Activity：Teprasiran (QPI-1002) is a small interfering RNA that temporarily inhibits p53-mediated cell death that underlies acute kidney injury (AKI). Research Area：Cancer Targets：Small Interfering RNA (siRNA)|MDM-2/p53 Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus; Related […]

For research use only. We do not sell to patients. MDM2/4-p53-IN-1 Biological Activity：MDM2/4-p53-IN-1 is a potent MDM2-p53 and MDM4-p53 inhibitor with IC50 values of 35.9, 57.4 nM, respectively. MDM2/4-p53-IN-1 shows antiproliferative activity. Research Area：Cancer Targets：MDM-2/p53 Related Small Molecules:MDM2-p53-IN-15;MC-VC-PABC-SP 141;p53 and MDM2 proteins-interaction-inhibitor (racemic);Navtemadlin;MD-224;Mutant p53 modulator-1;MDM2/4-p53-IN-2;MX69;p-nitro-Pifithrin-α;RG7112;MMRi62;Anticancer agent 50;NSC59984;Pifithrin-β hydrobromide;Ivaltinostat formic;GEM-5;Tenovin-6;PK11007;AM-8735;GN25;RO-5963;PhiKan 083;C16-Ceramide;Pifithrin-α hydrobromide;MA242;Anticancer agent 65;CBL0137 hydrochloride;HDAC-IN-34 Trending […]

For research use only. We do not sell to patients. P53R3 CAS No. : 922150-12-7 Biological Activity：P53R3 is a potent p53 reactivator and restores sequence-specific DNA binding of p53 hot spot mutants, including p53R175H, p53R248W and p53R273H. P53R3 induces p53-dependent antiproliferative effects with much higher specificity than PRIMA-1. P53R3 enhances the recruitment of wild-type p53 and […]