Tag: Modulator

For research use only. We do not sell to patients. Org 27569 CAS No. : 868273-06-7 Biological Activity：Org 27569 is a potent CB1 receptor allosteric modulator, which increases agonist binding, yet blocks agonist-induced CB1 signaling. Research Area：Neurological Disease Targets：Cannabinoid Receptor Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Neuronal Signaling Compound Library; Related Small Molecules:Pregnenolone […]

For research use only. We do not sell to patients. Cariprazine-d6 CAS No. : 1308278-67-2 Biological Activity：Cariprazine D6 (RGH-188 D6) is a deuterium labeled Cariprazine. Cariprazine Cariprazine is an antipsychotic agent that exhibits high affinity for the D3 (Ki of 0.085 nM) and D2 (Ki of 0.49 nM) receptors, and moderate affinity for the 5-HT1A […]

For research use only. We do not sell to patients. ADX71441 CAS No. : 1207440-88-7 Biological Activity：ADX71441 is a potent and selective positive allosteric modulator of the GABAB receptor. ADX71441 is bioavailable after oral administration and is brain penetrant. ADX71441 has the potential for research of anxiety, pain and spasticity. Research Area：Neurological Disease Targets：GABA Receptor […]

For research use only. We do not sell to patients. Incensole Acetate CAS No. : 34701-53-6 Biological Activity：Incensole acetate is a main constituent of Boswellia carterii resin, has neuroprotective effects against neuronal damage in traumatic and ischemic head injury. Incensole acetate reduces Aβ25–35-triggered apoptosis in hOBNSCs. Research Area：Neurological Disease Targets：Apoptosis Related Screening Libraries:Covalent Screening Library […]

For research use only. We do not sell to patients. Tinengotinib CAS No. : 2230490-29-4 Biological Activity：Tinengotinib is the modulator of one or more protein kinases such as Aurora kinase and VEGFR kinase. Tinengotinib has the potential for the research of these kinase abnormalities diseases mediated, especially cancer-related diseases (extracted from patent WO2018108079A1). Research Area：Cancer […]

For research use only. We do not sell to patients. Pulchinenoside A CAS No. : 129724-84-1 Biological Activity：Pulchinenoside A is a natural triterpenoid saponin that enhances synaptic plasticity in the adult mouse hippocampus and facilitates spatial memory in adult mice. In vitro: Additions of pulsatilloside A and anemoside A3, at dosages ranging from 0.1, 1 […]

For research use only. We do not sell to patients. Tegaserod-13C,d3 maleate Biological Activity：Tegaserod-13C,d3 (maleate) is the 13C- and deuterium labeled Tegaserod (maleate). Tegaserod maleate is a selective 5-HT4 receptor partial agonist and a 5-HT2B receptor antagonist. Tegaserod maleate exhibits a promotile effect throughout the gastrointestinal (GI) tract[2][5]. Research Area：Metabolic Disease|Neurological Disease Targets：5-HT Receptor Related […]

For research use only. We do not sell to patients. HBV-IN-17 CAS No. : 2270943-13-8 Biological Activity：HBV-IN-17 (compound 8) is a potent HBV capsid assembly modulator with an EC50 of 511 nM. Research Area：Infection Targets：HBV Related Small Molecules:DVR-01;Bicyclol;Catalpol;Schisantherin C;HBV-IN-20;Glycosmisic acid;Schisanwilsonin C;RO6889678;Thiamine hydrochloride;Evixapodlin;Canocapavir;HBV-IN-19;Bifendate-d6;(5S,8R)-HBV-IN-10;Punicalin;OSS_128167;3′-DMTr-dG(iBu);HBV-IN-8;HBV-IN-7;L-2′-Fd4C;AB-729;Hepatitis B Virus Core (128-140);Besifovir Dipivoxil maleate;AT-130;HBV-IN-4 Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  […]

For research use only. We do not sell to patients. Fibronectin CAS No. : 86088-83-7 Biological Activity：Fibronectin, a glycoprotein (~500 kDa) present in blood as well as in cells, is a biomarker of tissue injury. Fibronectin binds to membrane-spanning receptor proteins called integrins. Fibronectin also binds to other extracellular matrix proteins such as collagen, fibrin, […]