Tag: Antagonist

For research use only. We do not sell to patients. Oxprenolol-d7 hydrochloride CAS No. : 1189649-47-5 Biological Activity：Oxprenolol-d7 hydrochloride (Ba 39089-d7) is the deuterium labeled Oxprenolol hydrochloride. Oxprenolol hydrochloride (Ba 39089) is an orally bioavailable β-adrenergic receptor (β-AR) antagonist with a Ki of 7.10 nM in a radioligand binding assay using rat heart muscle. Research […]

For research use only. We do not sell to patients. KU14R CAS No. : 189224-48-4 Biological Activity：KU14R is a new I(3)-R antagonist, which selectively blocks the insulin secretory response to imidazolines. IC50 Value: Target: Insulin Receptor A new I(3)-R antagonist, KU14R (2 (2-ethyl 2,3-dihydro-2-benzofuranyl)-2-imidazole), which selectively blocks the insulin secretory response to imidazolines. KU14R partially […]

For research use only. We do not sell to patients. Mitiglinide CAS No. : 145375-43-5 Biological Activity：Mitiglinide (KAD-1229), an insulinotropic agent, is an ATP-sensitive K+ (KATP) channel antagonist. Mitiglinide is highly specific to the Kir6.2/SUR1 complex (the pancreatic beta-cell KATP channel). Mitiglinide can be used for the research of type 2 diabetes[2]. Research Area：Metabolic Disease […]

For research use only. We do not sell to patients. Sonepiprazole CAS No. : 170858-33-0 Biological Activity：Sonepiprazole (PNU-101387G) is a selective D4 dopamine antagonist with Kis of 3.6, 10.1, 5147, and 7430 nM for rD4-Dopamine, hD4.2-Dopamine, rD2-Dopamine, and Histamine-H1 receptors, respectively. Research Area：Neurological Disease Targets：Dopamine Receptor Related Small Molecules:Alizapride hydrochloride;Thioproperazine;Bromopride-d3;Nuciferine;Glaucine;SB-277011 dihydrochloride;MIF-1 TFA;Sulpiride;(Rac)-Razpipadon;Clebopride malate;WAY-100635;Flupentixol-d4 dihydrochloride;Cariprazine-d6 hydrochloride;Itopride-d6 […]

For research use only. We do not sell to patients. Glycopyrrolate-d5 bromide Biological Activity：Glycopyrrolate-d5 (bromide) is deuterium labeled Glycopyrrolate. Research Area：Neurological Disease Targets：mAChR Related Small Molecules:VU0357017 hydrochloride;TBPB;Imidafenacin;Sabcomeline;MK-6884;Brompheniramine-d6 maleate;Navafenterol saccharinate;DREADD agonist 21;Cyclobuxine D;Brompheniramine maleate;Dexetimide;Anisodamine hydrobromide;Anisotropine bromide;PD 102807;Nebracetam hydrochloride;Muscarine-d9 iodide;Mazaticol;VU0455691;Arborine;Oxitropium Bromide;Propiverine hydrochloride;VU0152099;MHP 133;YM-58790;Elucaine;Rispenzepine;Phenglutarimid;Rapacuronium bromide;Ambutonium bromide;Temiverine hydrochloride;Procyclidine;M4 mAChR agonist-1;Camylofine Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural […]

For research use only. We do not sell to patients. AZD1979 CAS No. : 1254035-84-1 Biological Activity：AZD1979 is a Melanin-concentrating hormone receptor 1 (MCHr1) antagonist with an IC50 of ~12 nM. Research Area：Metabolic Disease|Endocrinology Targets：MCHR1 (GPR24) Related Screening Libraries:Clinical Compound Library Plus;Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Neuronal Signaling Compound Library;Clinical Compound Library;Endocrinology Compound Library;Anti-Obesity […]

For research use only. We do not sell to patients. Proglumide CAS No. : 6620-60-6 Biological Activity：Proglumide is a nonpeptide and orally active cholecystokinin (CCK)-A/B receptors antagonist. Proglumide selective blocks CCK’s effects in the central nervous system (CNS). Proglumide has ability to inhibit gastric secretion and to protect the gastroduodenal mucosa. Proglumide also has antiepileptic […]

For research use only. We do not sell to patients. ADRA1D receptor antagonist 1 CAS No. : 1191908-14-1 Biological Activity：ADRA1D receptor antagonist 1 is a potent, selective and orally active α1D adrenoceptor antagonist, with a Ki of 1.6 nM. Research Area：Endocrinology Targets：Adrenergic Receptor Related Small Molecules:Todralazine;ARC 239 dihydrochloride;Yohimbine;Glaucine;Salbutamol;BI-167107;Talibegron hydrochloride;Arotinolol;SR59230A;Higenamine hydrochloride;Navafenterol saccharinate;Isoprenaline hydrochloride;Bevantolol;Zilpaterol-d7;Ritanserin;A55453;Povafonidine;β3-AR agonist 1;Tulobuterol;AGN 192836;KUC-7322;Oxyfedrine;Urapidil […]

For research use only. We do not sell to patients. NESS 0327 CAS No. : 494844-07-4 Biological Activity：NESS 0327 is a cannabinoid antagonist with high selectivity for the cannabinoid CB1 receptor. NESS 0327 is more than 60,000-fold selective for the CB1 receptor. Research Area：Neurological Disease Targets：Cannabinoid Receptor Related Small Molecules:Pregnenolone monosulfate sodium;GW842166X;RVD-Hpα TFA;β-Caryophyllene;Hemopressin(rat) TFA;AM8936;Taranabant;Bay 59-3074;CB1-IN-2;Olivetol;CB1/2 […]

For research use only. We do not sell to patients. Vorapaxar sulfate CAS No. : 705260-08-8 Biological Activity：Vorapaxar sulfate (SCH 530348 sulfate), an antiplatelet agent, is a selective, orally active, and competitive thrombin receptor protease-activated receptor (PAR-1) antagonist (Ki=8.1 nM). Vorapaxar sulfate inhibits thrombin receptor-activating peptide (TRAP)-induced platelet aggregation in a dose-dependent manner. Research Area：Cardiovascular […]