Tag: Antagonist

For research use only. We do not sell to patients. Huwentoxin XVI TFA Biological Activity：Huwentoxin XVI TFA, an analgesic, is a highly reversible and selective mammalian N-type calcium channel (IC50 of ~60 nM) antagonist from Chinese tarantula Ornithoctonus huwena. Huwentoxin XVI TFA has no effect on voltagegated T-type calcium channels, potassium channels or sodium channels. […]

For research use only. We do not sell to patients. Hydroxyzine D4 dihydrochloride Biological Activity：Hydroxyzine D4 dihydrochloride is deuterium labeled Hydroxyzine. Hydroxyzine is a heterocyclic histamine H1-receptor antagonist. Hydroxyzine has anticholinergic, anxiolytic and analgesic properties. Research Area：Endocrinology|Inflammation/Immunology|Neurological Disease Targets：Histamine Receptor Related Small Molecules:Tripelennamine;Brompheniramine-d6 maleate;Samelisant;Chlorphenoxamine;H3 receptor-MO-1;Diphenhydramine;ABT-239;Ketotifen fumarate;Ranitidine;Cetirizine;Diphenylpyraline hydrochloride;Loratadine-d5;Phenyltoloxamine;Ritanserin;BMY-25271;FRG8701;Mecamylamine hydrochloride;Cimetidine sulfoxide;Brompheniramine maleate;Tecastemizole;Famotidine-13C,d3;Bromazine-d6 hydrochloride Trending products：Recombinant Proteins  |  […]

For research use only. We do not sell to patients. Anisodamine hydrobromide CAS No. : 55449-49-5 Biological Activity：Anisodamine hydrobromide (6-Hydroxyhyoscyamine hydrobromide), a belladonna alkaloid, is a non-subtype-selective muscarinic and a nicotinic cholinoceptor antagonist. Anisodamine hydrobromide shows antioxidant, anti-inflammatory properties[2]. Research Area：Inflammation/Immunology Targets：mAChR Related Screening Libraries:Natural Product Library Plus;Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved […]

For research use only. We do not sell to patients. Raleukin CAS No. : 143090-92-0 Biological Activity：Raleukin (AMG-719) is a recombinant, nonglycosylated human interleukin-1 receptor (IL-1R) antagonist. Raleukin (AMG-719) is the first biological agent to block the pro-inflammatory effects[2]. Research Area：Cancer|Inflammation/Immunology Targets：Interleukin Related Related Screening Libraries:Drug Repurposing Compound Library Plus; FDA-Approved Drug Library Plus;Bioactive Compound […]

For research use only. We do not sell to patients. L-AP3 CAS No. : 23052-80-4 Biological Activity：L-AP3, metabotropic glutamate receptor (mGluR) antagonist, inhibits D-phosphoserine and L-phosphoserine with IC50s of 368 μM and 2087 μM, respectively. Research Area：Neurological Disease Targets：mGluR Related Small Molecules:LY3020371 hydrochloride;ZJ43;FPTQ;(S)-MCPG;mGluR2 modulator 1;VU6010572;Mavoglurant racemate;DFMTI;JNJ16259685;Auglurant;FITM;(-)-Camphoric acid;LY367385 hydrochloride;Cinnabarinic acid;LY379268;AZD 9272;mGluR2 antagonist 1;ABP688;FTIDC;MPPG;VU6001966;VU0155041 sodium;VU 0364439;trans-ACPD;AZD-8529 mesylate;VU […]

For research use only. We do not sell to patients. Carteolol-d9 hydrochloride CAS No. : 1346602-13-8 Biological Activity：Carteolol-d9 (OPC-1085-d9) hydrochloride is the deuterium labeled Carteolol hydrochloride. Carteolol hydrochloride (OPC-1085 hydrochloride) is a non-selective beta blocker used to treat glaucoma[2]. Research Area：Cardiovascular Disease|Endocrinology Targets：Adrenergic Receptor Related Small Molecules:Todralazine;ARC 239 dihydrochloride;Yohimbine;Glaucine;Salbutamol;BI-167107;Talibegron hydrochloride;Arotinolol;SR59230A;Higenamine hydrochloride;Navafenterol saccharinate;Isoprenaline hydrochloride;Bevantolol;Zilpaterol-d7;Ritanserin;A55453;Povafonidine;β3-AR agonist 1;Tulobuterol;AGN […]

For research use only. We do not sell to patients. Praeruptorin E CAS No. : 78478-28-1 Biological Activity：Praeruptorin E is a main bioactive constituent of Peucedanum praeruptorum (also known as Bai-Hua Qian Hu). Praeruptorin C is a calcium antagonist with pD2′ value of 5.2. Research Area：Cardiovascular Disease Targets：Calcium Channel Related Screening Libraries:Natural Product Library Plus;Bioactive […]

For research use only. We do not sell to patients. Xanthine amine congener dihydrochloride CAS No. : 1962928-23-9 Biological Activity：Xanthine amine congener dihydrochloride (XAC dihydrochloride) is a potent Adenosine A1 receptor and A2 receptor antagonist with IC50 values of 1.8 and 114 nM, respectively. Xanthine amine congener acts as a convulsant agent in mice model. Research […]

For research use only. We do not sell to patients. 6-Mercaptopurine hydrate CAS No. : 6112-76-1 Biological Activity：6-Mercaptopurine hydrate (Mercaptopurine hydrate; 6-MP hydrate) is a purine analogue which acts as an antagonist of the endogenous purines and has been widely used as antileukemic agent and immunosuppressive drug. Research Area：Cancer Targets：Nucleoside Antimetabolite/Analog Related Screening Libraries:Drug Repurposing […]

For research use only. We do not sell to patients. GR231118 TFA Biological Activity：GR231118 TFA, an analogue of the C-terminus of neuropeptide Y, is a potent , competitive and relative seletive antagonist at human neuropeptide YY receptor with a pKi of 10.4. GR231118 a potent agonist at the human neuropeptide YY4 receptor (pEC50=8.6; pKi=9.6) and […]