Tag: Agonist|Antagonist

For research use only. We do not sell to patients. Agomelatine hydrochloride CAS No. : 1176316-99-6 Biological Activity：Agomelatine hydrochloride (S-20098 hydrochloride) is a specific agonist of MT1 and MT2 receptors with Kis of 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, and HEK-hMT2, respectively. Agomelatine hydrochloride is a selective 5-HT2C receptor antagonist with […]

For research use only. We do not sell to patients. GPBAR1-IN-3 Biological Activity：GPBAR1-IN-3 (Compound 14) is a selective GPBAR1 agonist (EC50=0.17 μM) and a CysLT1R antagonist. Research Area：Neurological Disease|Others Targets：Leukotriene Receptor|G protein-coupled Bile Acid Receptor 1 Related Small Molecules:Pranlukast-d4;Verlukast-d6;Hyodeoxycholic acid-d5;Cholic acid 7-sulfate;Deoxycholic acid-13C;Ablukast;CP-96486;MK-886;BIIL-260 hydrochloride;Deoxycholic acid sodium hydrate;Pranlukast;Taurodeoxycholic acid sodium hydrate;γ-Linolenic acid ethyl ester;REV 5901;SBI-115;INT-767;U-75302;RS-601;Tipelukast;LM-1484;RG-12525;Quinotolast sodium;Darbufelone […]

For research use only. We do not sell to patients. Clozapine N-oxide dihydrochloride CAS No. : 2250025-93-3 Biological Activity：Clozapine N-oxide dihydrochloride is a major metabolite of Clozapine and a human muscarinic designer receptors (DREADDs) agonist. Clozapine N-oxide dihydrochloride activates the DREADD receptor hM3Dq and hM4Di. Clozapine N-oxide dihydrochloride can cross the blood-brain barrier[2][3][4]. Clozapine is […]

For research use only. We do not sell to patients. BMY 7378 CAS No. : 21102-95-4 Biological Activity：BMY 7378 is a selective antagonist of α1D-adrenoceptor (α1D-AR). BMY 7378 binds to membranes expressing the cloned rat α1D-AR with a >100-fold higher affinity (Ki=2 nM) than binding to either the cloned rat α1A-AR (Ki=800 nM) or the […]

For research use only. We do not sell to patients. Agomelatine-d4 CAS No. : 1079389-44-8 Biological Activity：Agomelatine-d4 (S-20098-d4) is the deuterium labeled Agomelatine. Agomelatine (S-20098) is a specific agonist of MT1 and MT2 receptors with Kis of 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, and HEK-hMT2, respectively. Agomelatine is a selective 5-HT2C […]

For research use only. We do not sell to patients. Neuropeptide EI, rat CAS No. : 125934-45-4 Biological Activity：Neuropeptide EI, rat displays functional melanin concentrating hormone (MCH)-antagonist and melanocyte-stimulating hormone (MSH) agonist activity in different behavioral paradigms. Research Area：Neurological Disease|Endocrinology Targets：MCHR1 (GPR24)|Melanocortin Receptor Related Small Molecules:SB-568849;Bremelanotide;MSG606 TFA;Resomelagon;Dersimelagon;Adrenocorticotropic Hormone (ACTH) (1-39), rat TFA;[Ala17]-MCH;Terrein;AZD1979;γ1-MSH TFA;SNT-207707;PF-07258669;THIQ;ACTH (11-24) (acetate);ALB-127158(a);JKC363 […]

For research use only. We do not sell to patients. Quetiapine-d4 fumarate CAS No. : 1287376-15-1 Biological Activity：Quetiapine D4 fumarate is the deuterium labeled Quetiapine fumarate. Quetiapine fumarate is a 5-HT receptors agonist and a dopamine receptor antagonist. Antidepressant and anxiolytic effects. Research Area：Neurological Disease Targets：Dopamine Receptor|5-HT Receptor Related Small Molecules:F 13714;Alizapride hydrochloride;Thioproperazine;Mosapride-d5;Bromopride-d3;Nuciferine;Glaucine;Renzapride;SB-277011 dihydrochloride;LY 344864 […]