BMY 7378

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BMY 7378

CAS No. : 21102-95-4

Biological Activity:BMY 7378 is a selective antagonist of α1D-adrenoceptor (α1D-AR). BMY 7378 binds to membranes expressing the cloned rat α1D-AR with a >100-fold higher affinity (Ki=2 nM) than binding to either the cloned rat α1A-AR (Ki=800 nM) or the hamster α1B-AR (Ki=600 nM). BMY 7378 is a 5-HT1A receptor partial agonist[2].

Research Area:Cardiovascular Disease

Targets:Adrenergic Receptor|5-HT Receptor

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