2023 - epigenetics modulation frontier

CYP1B1-IN-1

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. CYP1B1-IN-1 CAS No. : 842122-33-2 Biological Activity：CYP1B1-IN-1 (Compound 9e) is a selective cytochrome P450 1B1 (CYP1B1) inhibitor with an IC50 of 0.49 nM. Research Area：Cancer Targets：Cytochrome P450 Related Small Molecules:SR9186;AMG-208;CYP2C9/CYP2C19-IN-1;Hypericin;Galeterone;Ranitidine;Bergapten;Ginsenoside Rd;AS1810722;Isoglycycoumarin;Polygalaxanthone III;Phenyltoloxamine;Ezutromid;Seviteronel;β-Apo-8′-carotenal;Diosmetin-d3;EDP-305;Fipronil;Cholesterol 24-hydroxylase-IN-1;TMS;Harmalol hydrochloride;Olivetol Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | […]

Coumarin-3-carboxylic Acid

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. Coumarin-3-carboxylic Acid CAS No. : 531-81-7 Biological Activity：Coumarin-3-carboxylic acid (2- Oxochromene-3-carboxylic acid) is an important initial compound for the synthesis of coumarins which are well known natural products for their diverse biological activities. Lanthanide complexes of Coumarin-3-carboxylic acid exhibit antiproliferative activity towards K-562 cell line[2]. […]

TRPC5-IN-4

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. TRPC5-IN-4 Biological Activity：TRPC5-IN-4 is potent and safe TRPC inhibitor with IC50 value of 14.07 nM and 65 nM for TRPC5 and TRPC4, respectively. TRPC5-IN-4 shows no damage on the cellular component of liver and kidney. TRPC5-IN-4 can be used for the research of chronic kidney […]

Indole-3-carboxaldehyde

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. Indole-3-carboxaldehyde CAS No. : 487-89-8 Biological Activity：Indole-3-carboxaldehyde (3-Formylindole), a banlangen extract, is the product of the oxidative degradation of indole-3-acetic acid (IAA) by crude enzyme preparations from etiolated pea seedlings. Indole-3-carboxaldehyde (3-Formylindole) is a biochemical used to prepare analogs of the indole phytoalexin cyclobrassinin. Research […]

Glycohyodeoxycholic acid

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. Glycohyodeoxycholic acid CAS No. : 13042-33-6 Biological Activity：Glycohyodeoxycholic acid is a major metabolite of Hyodeoxycholic acid in humans. Glycohyodeoxycholic acid has preventative effects on gallstone formation[2]. Research Area：Metabolic Disease Targets：Endogenous Metabolite Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus;Metabolism/Protease Compound Library;Natural Product Library;Human Endogenous […]

CCT367766 formic

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. CCT367766 formic Biological Activity：CCT367766 formic is a potent and the third generation heterobifunctional and Cereblon-based pirin targeting protein degradation probe (PDP, or PROTAC), depletes pirin protein expression at low concentration. CCT367766 formic exhibits a moderate affinity for the CRBN-DDB1 complex with an IC50 value of […]

PGE-M

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. PGE-M CAS No. : 24769-56-0 Biological Activity：PGE-M is a metabolite of prostaglandin E2 (PEG2) as a biomarker of inflammation and cancer including advanced colorectal neoplasia, ovarian cancer, prostate cancer and so on. Urinary PGE-M is positively associated with obesity, smoking and lung metastases with breast […]

HCV-IN-38

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. HCV-IN-38 Biological Activity：HCV-IN-38 is a potent, selective and orally active HCV inhibitor (EC50=15 nM, SI=431). HCV-IN-38 has high anti-HCV activity and low cytotoxicity. HCV-IN-38 has a good safety and oral pharmacokinetic profile. Research Area：Infection Targets：HCV Related Small Molecules:HCV-IN-30;Sennidin A;HCV-IN-31;Radalbuvir;Grazoprevir potassium salt;FGI-106 tetrahydrochloride;BMS-986144;Oenothein B;Triton X-45(n=4);Mecarbinate;Artemisinin-d3;TTP-8307;HCV-IN-34;Miravirsen;Ciluprevir;MK-0608;Setrobuvir;Astodrimer;Elbasvir Trending […]

Brinzolamide

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. Brinzolamide CAS No. : 138890-62-7 Biological Activity：Brinzolamide (AL-4862) is a selective carbonic anhydrase II inhibitor with anIC50 value of 3.2 nM. Brinzolamide hydrochloride reduces intraocular pressure (IOP) by inhibiting ciliary CA-II and decreasing atrial fluid secretion. Brinzolamide can be used in glaucoma disease research[2]. Research […]

3-Pyridineacetic acid

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. 3-Pyridineacetic acid CAS No. : 501-81-5 Biological Activity：3-Pyridineacetic acid is a higher homologue of nicotinic acid, a breakdown product of nicotine (and other tobacco alkaloids)[2]. Research Area：Others Targets：Endogenous Metabolite Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus;Metabolism/Protease Compound Library;Natural Product Library;Fragment Library;Food-Sourced Compound Library […]