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CAS No. : 1002304-34-8

Biological Activity:AMG-208 is an orally active c-Met/RON dual selective inhibitor with an IC50 of 9 nM for c-Met. AMG-208 is a CYP3A4 inhibitor with an IC50 of 32 μM. AMG-208 has anti-cancer activity[2][3].

Research Area:Cancer

Targets:c-Met/HGFR|Cytochrome P450

Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Kinase Inhibitor Library;Metabolism/Protease Compound Library;Protein Tyrosine Kinase Compound Library;Anti-Cancer Compound Library;Clinical Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Antioxidant Compound Library;Oxygen Sensing Compound Library;Anti-COVID-19 Compound Library;Orally Active Compound Library;Anti-Lung Cancer Compound Library;Angiogenesis-Related Compound Library;Anti-Liver Cancer Compound Library ;Anti-Colorectal Cancer Compound Library ;Anti-Prostate Cancer Compound Library;Cancer Stem Cells Compound Library;

Related Small Molecules:SR9186;D6808;CYP1B1-IN-1;MET kinase-IN-2;CYP2C9/CYP2C19-IN-1;c-Met-IN-9;Hypericin;Tyrosine kinase-IN-4;Savolitinib;Galeterone;Ranitidine;Bergapten;Foretinib;Ginsenoside Rd;PF-04217903 phenolsulfonate;AS1810722;Isoglycycoumarin;Polygalaxanthone III;Phenyltoloxamine;Ezutromid;Seviteronel;β-​Apo-​8′-​carotenal;Diosmetin-d3;EDP-305

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