BI-135585

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BI-135585

CAS No. : 1114561-85-1

Biological Activity:BI-135585 is a potent, selective and orally active 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) inhibitor with an IC50 of 13 nM. BI-135585 exhibits >1000-fold selectivity over other hydroxysteroid dehydrogenases. BI-135585 can be used for type 2 diabetes research[2].

Research Area:Metabolic Disease

Targets:11β-HSD

Related Small Molecules:AZD8329;ABT-384;(R)-BMS-816336;Carbenoxolone disodium;11β-HSD1-IN-1;Emodin-d4;HSD-016;BVT 2733;11β-HSD1-IN-6;Carbenoxolone-d4;AZD 4017;Necroptosis-IN-3;11β-HSD1-IN-11;BVT-14225;Emodin;INCB13739;AMG-221

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