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Biological Activity:CALP2 TFA is a calmodulin (CaM) antagonist (Kd of 7.9 µM) with high affinity for binding to the CaM EF-hand/Ca2+-binding site. CALP2 TFA inhibits CaM-dependent phosphodiesterase activity and increases intracellular Ca2+ concentrations. CALP2 TFA potently inhibits of adhesion and degranulation. CALP2 TFA is also a strong activator of alveolar macrophages[2][3][4].

Research Area:Inflammation/Immunology


Related Screening Libraries:Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Membrane Transporter/Ion Channel Compound Library;Peptide Library;

Related Small Molecules:Psoralenoside;CALP1;CV-159;W-7 hydrochloride;Calmodulin antagonist-1;Calmodulin Binding Peptide 1;Acremonidin A;CALP2;Neurogranin (48-76), mouse;Stains-All;Metofenazate;Acremoxanthone C

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  • Structurally and synthetically diverse biologically active compounds;

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