Tag: Modulator

For research use only. We do not sell to patients. Dihydroergotoxine mesylate CAS No. : 8067-24-1 Biological Activity：Dihydroergotoxine mesylate is a complex of closely related alkaloid salts; Binds with high affinity to the GABAA receptor Cl- channel, producing an allosteric interaction with the benzodiazepine site. IC50 value: Target: Dihydroergotoxine mesylate also interacts with central dopaminergic, […]

For research use only. We do not sell to patients. Betamethasone dipropionate-d10 CAS No. : 2280940-19-2 Biological Activity：Betamethasone dipropionate-d10 (Betamethasone 17-d10,21-dipropionate-d10) is the deuterium labeled Betamethasone dipropionate. Betamethasone dipropionate is a glucocorticoid steroid with anti-inflammatory and immunosuppressive abilities. Research Area：Inflammation/Immunology|Endocrinology|Cancer Targets：Glucocorticoid Receptor Related Small Molecules:Deflazacort-D5;Glucocorticoid receptor agonist-2;AZD2906;Beclometasone dipropionate;ORIC-101;Clobetasone butyrate;Cortisone-d2;Clobetasone butyrate-d7;Cortisone-13C3;Glucocorticoid receptor agonist;Cortodoxone-d2;Hydrocortisone aceponate;Glucocorticoid receptor-IN-2;OP-3633;GW-870086;Nenocorilant;Hydrocortisone cypionate;Corticosterone-d8;21-Acetoxypregna-1,4,9(11),16-tetraene-3,20-dione;Deflazacort-d5-1;Mapracorat;Hydrocortisone-d4;Hydrocortisone […]

For research use only. We do not sell to patients. mGluR5 modulator 1 CAS No. : 1261171-52-1 Biological Activity：mGluR5 modulator 1 is a mGluR5 positive allosteric modulator. mGluR5 modulator 1 can be used for the research of the schizophrenia and cognitive impairments. Research Area：Neurological Disease Targets：mGluR Related Small Molecules:LY3020371 hydrochloride;ZJ43;FPTQ;(S)-MCPG;mGluR2 modulator 1;VU6010572;Mavoglurant racemate;DFMTI;JNJ16259685;Auglurant;FITM;(-)-Camphoric acid;LY367385 hydrochloride;Cinnabarinic […]

For research use only. We do not sell to patients. Cariprazine hydrochloride CAS No. : 1083076-69-0 Biological Activity：Cariprazine hydrochloride is a novel antipsychotic drug candidate that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki=2.6 nM). Research Area：Neurological Disease Targets：Dopamine Receptor|5-HT Receptor Related […]

For research use only. We do not sell to patients. IL-17A modulator-3 CAS No. : 2467732-95-0 Biological Activity：IL-17A modulator-3 (compound 253) is a IL-17A modulator. IL-17A modulator-3 inhibits IL-17A/A with an IC50 value ＜10 μM. IL-17A modulator-3 can be used for the research of inflammation, cancer and autoimmune disease. Research Area：Cancer|Inflammation/Immunology Targets：Interleukin Related Related Small […]

For research use only. We do not sell to patients. Sipagladenant CAS No. : 858979-50-7 Biological Activity：Sipagladenant (Compound I) is an orally active adenosine receptor A2A inverse agonist. Sipagladenant can be used in frontal lobe dysfunction research[2]. Research Area：Neurological Disease Targets：Adenosine Receptor Related Small Molecules:MRS 1523;APNEA;MIPS521;Derenofylline;FSCPX;Theobromine-d3;Inosine-13C;Norisoboldine;N-0861 racemate;Xanthine amine congener dihydrochloride;LUF6096;A1/A3 AR antagonist 1;ATL-801;Istradefylline;Doxofylline-d6;A1AR antagonist 3;MRS1186;A2A/A3 AR […]

For research use only. We do not sell to patients. Raloxifene-d4 CAS No. : 1185076-44-1 Biological Activity：Raloxifene-d4 is the deuterium labeled Raloxifene. Raloxifene (Keoxifene) is a benzothiophene-derived selective estrogen receptor modulator (SERM). Raloxifene has estrogen-agonistic effects on bone and lipids and estrogen-antagonistic effects on the breast and uterus. Raloxifene is used for breast cancer and […]

For research use only. We do not sell to patients. gamma-secretase modulator 1 CAS No. : 1172637-87-4 Biological Activity：γ-secretase inhibitior-1 is a gamma-secretase modulator, γ-secretase inhibitior-1 is useful for Alzheimer’s disease. Research Area：Neurological Disease Targets：γ-secretase Related Screening Libraries:Bioactive Compound Library Plus; Related Small Molecules:γ-Secretase modulator 4;ELN318463;Crenigacestat;Aβ42-IN-1 free base;Fosciclopirox;JNJ-40418677;gamma-secretase modulator 3;γ-Secretase modulator 11 hydrochloride;γ-Secretase modulator 12;Aβ42-IN-2;DAPT […]

For research use only. We do not sell to patients. Flibanserin-d4 CAS No. : 2122830-90-2 Biological Activity：Flibanserin D4 is a deuterium labeled Flibanserin (BIMT-17). Flibanserin is a full agonist of the serotonin 5-HT1A receptor (Ki=1 nM) and an antagonist of 5-HT2A (49 nM). Research Area：Neurological Disease Targets：5-HT Receptor Related Small Molecules:F 13714;Mosapride-d5;Nuciferine;Renzapride;LY 344864 racemate;Harmine hydrochloride;Valerenic […]

For research use only. We do not sell to patients. Toremifene-d6 Biological Activity：Toremifene-d6 is deuterium labeled Toremifene. Toremifene (Z-Toremifene) is a second-generation selective estrogen-receptor modulator (SERM) in development for the prevention of osteoporosis. Toremifene also potent inhibits infectious EBOV Zaire and Marburg (MARV) with IC50 of 0.07 µM and 2.6 µM, respectively[2]. Research Area：Cancer|Infection Targets：Estrogen […]