Tag: Modulator

For research use only. We do not sell to patients. [D-Trp11]-Neurotensin CAS No. : 73634-68-1 Biological Activity：[D-Trp11]-Neurotensin, an analogue of Neurotensin (NT), is a selective antagonist of NT in perfused rat hearts but behaves as a full agonist in guinea pig atria and rat stomach strips. [D-Trp11]-Neurotensin can inhibit NT-induced hypotension[2]. Research Area：Neurological Disease Targets：Neurotensin […]

For research use only. We do not sell to patients. E 2012 CAS No. : 870843-42-8 Biological Activity：E 2012 is a potent gamma (γ) secretase modulator without affecting Notch processing. E 2012 inhibits 3β-hydroxysterol Δ24-reductase (DHCR24) at the final step in the cholesterol biosynthesis. E 2012 aims at Alzheimer’s disease by reduction of amyloid β-42, […]

For research use only. We do not sell to patients. Methyl-3β-hydroxycholenate CAS No. : 20231-57-6 Biological Activity：Methyl-3β-hydroxycholenate is a ROR gamma modulator extracted from patent US20110263046 A1, in figure 2. Research Area：Inflammation/Immunology Targets：ROR Related Small Molecules:RORγt inhibitor 1;GNE-6468;SR3335;RORγt inverse agonist 30;GNE-0946;RORγt inverse agonist 13;Vimirogant hydrochloride;SR2211;Bevurogant;ROR agonist-1;RORγt Inverse agonist 8;CD12681;S18-000003;RORγt inhibitor 2;XY018;RORγt inverse agonist 29;SR1001;Cedirogant;SHR168442;ARN-6039;A-9758;Cintirorgon;Nobiletin;TAK-828F;RORγt inverse […]

For research use only. We do not sell to patients. (R)-ADX-47273 CAS No. : 851881-59-9 Biological Activity：(R)-ADX-47273 is a potent mGluR5 positive allosteric modulator, with an EC50 of 168 nM for potentiation . Research Area：Neurological Disease Targets：mGluR Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Neuronal Signaling Compound Library;Neurotransmitter Receptor Compound Library; Related Small Molecules:LY3020371 […]

For research use only. We do not sell to patients. DS34942424 Biological Activity：DS34942424 is an orally potent analgesic without mu opioid receptor agonist activity. Research Area：Neurological Disease Targets：Opioid Receptor Related Small Molecules:ORL1 antagonist 1;Loperamide-d6 N-Oxide;Deltorphin 2 TFA;Nalfurafine;β-Lipotropin (60-65);GSK1521498 free base;Trimebutine-d5 fumarate;Dynorphin B (1-13) (TFA);Dermorphin Analog;β-Endorphin (6-31), human;JTC-801;Valorphin;Corydaline;TAN-452;Matrine;Naloxonazine dihydrochloride;[Leu5]-Enkephalin;Sec-O-Glucosylhamaudol;DPDPE;EST73502;CTOP;β-Endorphin, equine;Tyr-W-MIF-1;Nociceptin (1-13), amide TFA;Morphiceptin;[Nphe1]Nociceptin(1-13)NH2;UFP-101 Trending products：Recombinant Proteins  […]

For research use only. We do not sell to patients. IL-17 modulator 1 disodium CAS No. : 2446803-91-2 Biological Activity：IL-17 modulator 1 (disodium) is an orally active, highly efficacious IL-17 modulator extracted from patent WO 2020127685. IL-17 modulator 1 (disodium) can be used for the research of diseases including psoriasis, ankylosing spondylitis and psoriatic arthritis. […]

For research use only. We do not sell to patients. VU0080241 CAS No. : 393845-24-4 Biological Activity：VU0080241 is a positive allosteric modulator (PAM) of the metabotropic glutamate receptor subtype 4 (mGluR4), with an EC50 of 4.6 μM. Research Area：Neurological Disease Targets：mGluR Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Neuronal Signaling Compound Library;Neurotransmitter Receptor Compound […]

For research use only. We do not sell to patients. RORγt modulator 2 CAS No. : 2247083-47-0 Biological Activity：RORγt modulator 2 (Compound 21) is a modulator of retinoid-related orphan receptor γt (RORγt) with the IC50 of

For research use only. We do not sell to patients. DOTA Zoledronate CAS No. : 1908409-18-6 Biological Activity：DOTA Zoledronate is a next-generation agent for bone targeted radionuclide therapy for diagnosing bone metastases. Research Area：Cancer Targets：Others Related Small Molecules:Immune initiator-1;Obiltoxaximab;DIBAC-GGFG-NH2CH2-Dxd;Cyanine5.5 maleimide chloride;Cymarin;Z-Glycine;2-Deoxy-2-fluoro-D-glucose-13C,d7;Water-18O;Fmoc-N-Me-D-Ala-OH;3,5-Diiodo-L-tyrosine;N3-Pen-Dde;Zimeldine-d6;Ornidazole diol;Nylidrin hydrochloride;PFI-653;N-Arachidonoyl Taurine-d4;OVA Peptide (323-339);((3-Fluorophenyl)sulfonyl)glycine;7ß-Hydroxycholesterol-d7;MALAT1-IN-1;Sibiricose A1;Mefruside-d3;Ethacrynic acid mercapturate-d3;FLAG peptide;Neocurdione Trending products：Recombinant Proteins  |  Bioactive […]

For research use only. We do not sell to patients. Zavacorilant CAS No. : 1781245-13-3 Biological Activity：Zavacorilant is capable of modulating glucocorticoid receptor (GR). Research Area：Metabolic Disease Targets：Glucocorticoid Receptor Related Small Molecules:Deflazacort-D5;Glucocorticoid receptor agonist-2;AZD2906;Beclometasone dipropionate;ORIC-101;Clobetasone butyrate;Cortisone-d2;Clobetasone butyrate-d7;Cortisone-13C3;Glucocorticoid receptor agonist;Cortodoxone-d2;Hydrocortisone aceponate;Glucocorticoid receptor-IN-2;OP-3633;GW-870086;Nenocorilant;Hydrocortisone cypionate;Corticosterone-d8;21-Acetoxypregna-1,4,9(11),16-tetraene-3,20-dione;Deflazacort-d5-1;Mapracorat;Hydrocortisone-d4;Hydrocortisone acetate Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  |  Fluorescent […]