Tag: Modulator

For research use only. We do not sell to patients. Betahistine EP Impurity C CAS No. : 5452-87-9 Biological Activity：Betahistine EP Impurity C (NSC19005) is an impurity of Betahistine. Betahistine is a potent, orally active and well-tolerated histamine H1 receptor agonist and H3 receptor antagonist used for the study of rheumatoid arthritis (RA)[2][3]. Research Area：Inflammation/Immunology […]

For research use only. We do not sell to patients. Flibanserin-d4-1 CAS No. : 2122830-91-3 Biological Activity：Flibanserin-d4-1 is deuterium labeled Flibanserin. Flibanserin (BIMT-17) is a full agonist of the serotonin 5-HT1A receptor (Ki=1 nM) and an antagonist of 5-HT2A (49 nM). Flibanserin binds to dopamine D4 receptors (4-24 nM), and has negligible affinity for a […]

For research use only. We do not sell to patients. Betamethasone dipropionate CAS No. : 5593-20-4 Biological Activity：Betamethasone dipropionate is a glucocorticoid steroid with anti-inflammatory and immunosuppressive abilities. Research Area：Inflammation/Immunology|Endocrinology|Cancer Targets：Glucocorticoid Receptor Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;FDA-Approved Drug Library;Anti-Cancer Compound Library;Drug Repurposing […]

For research use only. We do not sell to patients. Golcadomide CAS No. : 2379572-34-4 Biological Activity：Golcadomide (CC-99282) is a potent and orally active cereblon (CRBN) E3 ligase modulator (CELMoD). Golcadomide co-opts CRBN to induce potent and targeted degradation of Ikaros and Aiolos. Golcadomide can be used for researching non-Hodgkin lymphomas. Research Area：Cancer Targets：Ligands for […]

For research use only. We do not sell to patients. Rovazolac CAS No. : 1454288-88-0 Biological Activity：Rovazolac is a liver x receptor (LXR) modulator extracted from patent WO2013130892A1. Research Area：Inflammation/Immunology Targets：LXR Related Screening Libraries:Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Metabolism/Protease Compound Library;Lipid Metabolism Compound Library ;Nuclear Receptor Compound Library; Related Small Molecules:XL041;BE1218;DMHCA;Saikosaponin A;27-Hydroxycholesterol;LXRβ agonist-3;RGX-104;24(S)-Hydroxycholesterol;SR9238;BMS-779788;SR9243;AZ876;T0901317;LXRβ agonist-2;GSK2033;LXR antagonist […]

For research use only. We do not sell to patients. GPR120 modulator 1 CAS No. : 1050506-75-6 Biological Activity：GPR120 modulator 1 is a G protein coupled receptor 120 (GPR120) modulator extracted from patent US8394841B2, compound example F1. GPR120 modulator 1 can be used for the research of diseases associated with abnormal or deregulated GPR120, such […]

For research use only. We do not sell to patients. RORγt modulator 4 CAS No. : 2188177-73-1 Biological Activity：RORγt modulator 4 is a RORγt modulator. RORγt modulator 4 has an activity to modulate IL-17A production in cells derived from mouse spleen (WO2018030550A1; compound 146). Research Area：Cancer|Inflammation/Immunology Targets：ROR Related Small Molecules:RORγt inhibitor 1;GNE-6468;SR3335;RORγt inverse agonist 30;GNE-0946;RORγt […]

For research use only. We do not sell to patients. 11-Hydroxysugiol CAS No. : 88664-08-8 Biological Activity：11-Hydroxysugiol regulates the SUMOylation of intracellular receptors by modulating RARα and vitamin D3 receptor (VDR). Research Area：Infection Targets：RAR/RXR|VD/VDR Related Small Molecules:AGN 193109-d7;Atocalcitol;Retinoic acid;VD3-d6;Dihydrotachysterol;Tacalcitol;Impurity F of Calcipotriol;AC-261066;MeTC7;(24R)-MC 976;VDR agonist 1;TEI-9648;Magnolol;CB1151;ER 50891;(+)-Talarozole;MC 1046;1alpha, 25-Dihydroxy VD2-13C2;Secalciferol;Trifarotene;β-Apo-13-carotenone Trending products：Recombinant Proteins  |  Bioactive Screening […]

For research use only. We do not sell to patients. Etiocholanolone-d5 CAS No. : 1620102-33-1 Biological Activity：Etiocholanolone-d5 is the deuterium labeled Etiocholanolone. Etiocholanolone (5β-Androsterone) is the excreted metabolite of testosterone and has anticonvulsant activity. Etiocholanolone is a less potent neurosteroid positive allosteric modulator (PAM) of the GABAA receptor than its enantiomer form[2]. Research Area：Neurological Disease Targets：GABA Receptor|Endogenous Metabolite Related […]

For research use only. We do not sell to patients. GLPG0492 CAS No. : 1215085-92-9 Biological Activity：GLPG0492 is a non-steroidal selective androgen receptor modulator (potency 12 nM). GLPG0492 has the potential for the research of musculo-skeletal diseases such as sarcopenia and cachexia[2]. Research Area：Others Targets：Androgen Receptor Related Screening Libraries:Clinical Compound Library Plus;Bioactive Compound Library Plus;Clinical […]