Tag: Modulator

For research use only. We do not sell to patients. BMS-986121 CAS No. : 313671-26-0 Biological Activity：BMS-986121 is a positive allosteric modulator (PAM) of the μ opioid receptor extracted from patent WO2014107344. BMS-986121 is built on a chemical scaffold representing a new chemotype for μ receptor PAMs[2][3]. Research Area：Neurological Disease Targets：Opioid Receptor Related Small Molecules:ORL1 […]

For research use only. We do not sell to patients. ALLO-1 CAS No. : 37468-32-9 Biological Activity：ALLO-1, an autophagy receptor, is essential for autophagosome formation around paternal organelles and directly binds to the worm LC3 homologue LGG-1 through its LC3-interacting region (LIR) motif. Research Area：Cancer Targets：Autophagy Related Small Molecules:Physalin A;Stauprimide;Pregnenolone monosulfate sodium;Notoginsenoside Fc;AGN 193109-d7;AT9283;Ciclopirox-d11;BIX-01294;Wogonoside;Cyclovirobuxine D;Clotrimazole-d5;Curcumin;Loperamide-d6 […]

For research use only. We do not sell to patients. Ro 01-6128 CAS No. : 302841-86-7 Biological Activity：Ro 01-6128 is a positive allosteric modulator of mGluR1. Research Area：Neurological Disease Targets：mGluR Related Small Molecules:LY3020371 hydrochloride;ZJ43;FPTQ;(S)-MCPG;mGluR2 modulator 1;VU6010572;Mavoglurant racemate;DFMTI;JNJ16259685;Auglurant;FITM;(-)-Camphoric acid;LY367385 hydrochloride;Cinnabarinic acid;LY379268;AZD 9272;mGluR2 antagonist 1;ABP688;FTIDC;MPPG;L-AP3;VU6001966;VU0155041 sodium;VU 0364439;trans-ACPD;AZD-8529 mesylate;VU 0357121;PHCCC;HexylHIBO;VU0650786 Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  […]

For research use only. We do not sell to patients. Mitochonic acid 5 CAS No. : 1354707-41-7 Biological Activity：Mitochonic acid 5 binds mitochondria and ameliorates renal tubular and cardiac myocyte damage. Mitochonic acid 5 modulates mitochondrial ATP synthesis. Research Area：Cardiovascular Disease Targets：Mitochondrial Metabolism Related Screening Libraries:Bioactive Compound Library Plus;Metabolism/Protease Compound Library;Stem Cell Signaling Compound Library;Anti-Aging […]

For research use only. We do not sell to patients. Guignardone L CAS No. : 1821386-10-0 Biological Activity：Guignardone L is a metabolite isolated from the endophytic fungus Guignardia mangiferae with toll-like receptor 3 regulating activity. Research Area：Infection Targets：Toll-like Receptor (TLR) Related Small Molecules:C29;TMX-201;RS 09;ODN 20844;TLR7/8-IN-1;TLR8 agonist 5;Sulfo-ara-F-NMN;TLR7/8 antagonist 1;Gardiquimod;PF-4878691;Tri(TLR4-IN-C34-PEG2-amide-PEG1)-amide-C3-COOH;Pepinh-TRIF TFA;Afimetoran;Schaftoside;ODN 2088;CU-CPT22;UC-1V150;Diprovocim-X;CL264;MMG-11 quarterhydrate;CU-CPT 4a;TLR7/8 agonist 4;SM-324405;Enpatoran […]

For research use only. We do not sell to patients. ML254 CAS No. : 1428630-86-7 Biological Activity：ML254 is a potent mGlu5 potentiator, with EC50 and pEC50 of 9.3 nM and 8.03 nM for rat mGlu5, respectively. ML254 can be used for researching schizophrenia. Research Area：Neurological Disease Targets：mGluR Related Small Molecules:LY3020371 hydrochloride;ZJ43;FPTQ;(S)-MCPG;mGluR2 modulator 1;VU6010572;Mavoglurant racemate;DFMTI;JNJ16259685;Auglurant;FITM;(-)-Camphoric acid;LY367385 […]

For research use only. We do not sell to patients. Heterophyllin B CAS No. : 145459-19-4 Biological Activity：Heterophyllin B is an active cyclic peptide isolated from Pseudostellaria heterophylla. Heterophyllin B provides a novel strategy for the treatment of esophageal cancer. Research Area：Cancer Targets：PI3K Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus;Kinase Inhibitor Library;PI3K/Akt/mTOR Compound […]

For research use only. We do not sell to patients. BP 897 hydrochloride CAS No. : 314776-92-6 Biological Activity：BP 897 hydrochloride is a potent and partial dopamine D3 receptor agonist and a weak D2 receptor antagonist. BP 897 hydrochloride displays a high affinity at the dopamine D3 receptor (Ki=0.92 nM) and a 70 times lower […]

For research use only. We do not sell to patients. MRGPRX4 modulator-1 CAS No. : 2492596-61-7 Biological Activity：MRGPRX4 modulator-1 (compound 31-2) is a potent mas-related g-protein receptor X4 (MRGPR X4) modulator, with antagonist activity of IC50 < 100 nM for MRGPR4. MRGPRX4 modulator-1 can be used for researching MRGPR X4 dependent diseases such as itch, […]

For research use only. We do not sell to patients. IL-17 modulator 5 CAS No. : 2724206-27-1 Biological Activity：IL-17 modulator 5 (compound 26) is a IL-17 inhibitor, with an IC50 of 1 nM. Research Area：Inflammation/Immunology Targets：Interleukin Related Related Small Molecules:AX-024;Ginsenoside F3;Perakizumab;PNRI-299;CTX-471;Ac-YVAD-CHO;Deucravacitinib;Mulberroside A;NFAT Transcription Factor Regulator-1;IL-17A antagonist 1;Kansuinine B;Ginsenoside Rc;5(S)15(S)-DiHETE;IL-17A inhibitor 2;Anti-Mouse IL-1b Antibody;Raleukin;Ossirene;VGX-1027;RCGD423;Clazakizumab;Reslizumab;Gamma-glutamylcysteine TFA;Tyrphostin A1;Interleukin […]