Tag: Modulator

For research use only. We do not sell to patients. tCFA15 CAS No. : 220757-88-0 Biological Activity：tCFA15 is a trimethyl cyclohexenonic long chain fatty alcohol containing 15 carbon atoms on the side chain, promotes the differentiation of neurons, and may regulates Notch signaling. Research Area：Neurological Disease Targets：Notch Related Screening Libraries:Bioactive Compound Library Plus;Neuronal Signaling Compound […]

For research use only. We do not sell to patients. TPA-023B CAS No. : 425377-76-0 Biological Activity：TPA-023B is a high-affinity and orally active GABAA receptor α2/α3 subtype (Kis of 0.73 nM/2 nM) partial agonist and a α1 subtype (Ki of 1.8 nM) antagonist. TPA-023B has non-sedating anxiolytic-like properties. Research Area：Neurological Disease Targets：GABA Receptor Related Small […]

For research use only. We do not sell to patients. TRPC5 modulator-1 CAS No. : 1877343-90-2 Biological Activity：TRPC5 modulator-1 (Compound 9) is a TRPC5 modulator with an IC50 of

For research use only. We do not sell to patients. NLRP3 modulators 1 CAS No. : 2143015-87-4 Biological Activity：NLRP3 modulators 1 is the potent modulator of NLRP3. NLRP3 modulators 1 agonizes or partially agonizes NLRP3 that are useful for researching a condition, disease or disorder in which a decrease in LRP3 activity contributes to the […]

For research use only. We do not sell to patients. MA-0204 CAS No. : 2095128-17-7 Biological Activity：MA-0204 is a potent, highly selective and orally available peroxisome proliferator activated receptor δ (PPARδ) modulator with EC50s of 0.4 nM, 7.9 nM and 10 nM for human, mouse and rat PPARδ, respectively. Potential treatment for Duchene Muscular Dystrophy […]

For research use only. We do not sell to patients. VU6012962 CAS No. : 2313526-86-0 Biological Activity：VU6012962 is an orally bioavailable and CNS-penetrant metabotropic glutamate receptor 7 negative allosteric modulator (mGlu7 NAM) with an IC50 of 347 nM. Research Area：Neurological Disease Targets：mGluR Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Neuronal Signaling Compound Library;CNS-Penetrant Compound […]

For research use only. We do not sell to patients. A1AT modulator 2 CAS No. : 2555004-05-0 Biological Activity：A1AT modulator 2 (compound 33) is a modulator of A1AT (α-1 antitrypsin) with an IC50 value of ＞1.0 μM and an EC50 value of ＜0.4 μM. A1AT modulator 2 can be used for the research of infection […]

For research use only. We do not sell to patients. (E)-4-Hydroxytamoxifen-d5 CAS No. : 2470232-57-4 Biological Activity：(E)-4-Hydroxytamoxifen-d5 ((E)-Afimoxifene-d5) is the deuterium labeled (E)-4-Hydroxytamoxifen. (E)-4-Hydroxytamoxifen ((E)-Afimoxifene), the less active isomer of (Z)-4-hydroxytamoxifen, is an estrogen receptor modulator. Research Area：Cancer Targets：Estrogen Receptor/ERR Related Small Molecules:DS20362725;LSD1/ER-IN-1;Giredestrant;Avobenzone;Estriol-d3;Chrysin;ERRγ Inverse Agonist 1;(R)-DPN;MPP hydrochloride;GPR30 agonist-1;Diethylstilbestrol;Endoxifen;Glicoricone;ERB-196;Dihydroresveratrol;FLTX1;(Rac)-Hexestrol-d6 Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  […]

For research use only. We do not sell to patients. Flindokalner CAS No. : 187523-35-9 Biological Activity：Flindokalner (BMS-204352) is a potassium channel modulator. Flindokalner is a positive modulator of all neuronal Kv7 channel subtypes expressed in HEK293 cells. Flindokalner is also a large conductance calcium-activated K channel (BKca) positive modulator. Flindokalner shows a negative modulatory […]

For research use only. We do not sell to patients. PPARγ/δ modulator 1 CAS No. : 2089159-00-0 Biological Activity：PPARγ/δ modulator 1 (compound 3e) is a potent PPAR modulator. PPARγ/δ modulator 1 is a PPARδ antagonist and a PPARγ partial agonist , with Ki values of 14.4 nM and 5.31 μM, respectively. PPARγ/δ modulator 1 has […]