Tag: Modulator

For research use only. We do not sell to patients. 5-HT1A modulator 1 CAS No. : 142477-34-7 Biological Activity：5-HT1A modulator 1 displays very high affinities for the 5HT1A, adrenergic α1 and dopamine D2 receptor with IC50s of 2 ±0.3 nM, 10 ± 3 nM and 40 ±9 nM, respectively. Research Area：Neurological Disease Targets：5-HT Receptor Related […]

For research use only. We do not sell to patients. 4-Hydroxytamoxifen CAS No. : 68047-06-3 Biological Activity：4-Hydroxytamoxifen ((Z)-4-Hydroxytamoxifen) is an orally active, selective estrogen receptor modulator (SERM). 4-Hydroxytamoxifen ((Z)-4-Hydroxytamoxifen) induces CRISPR/Cas9 systems based on ER mediated nucleus translocation[2][3][4]. Research Area：Cancer Targets：Estrogen Receptor/ERR Related Screening Libraries:Natural Product-like Compound Library;Bioactive Compound Library Plus;Anti-Cancer Compound Library;Orally Active Compound […]

For research use only. We do not sell to patients. Eltoprazine hydrochloride CAS No. : 98206-09-8 Biological Activity：Eltoprazine hydrochloride (DU 28853 hydrochloride) is a serenic or antiaggressive agent which as an agonist at the 5-HT1A and 5-HT1B receptors and as an antagonist at the 5-HT2C receptor. IC50 value: Target: 5-HT1A/1B agonist; 5-HT2C antagonist in vitro: […]

For research use only. We do not sell to patients. 2,2,5,7,8-Pentamethyl-6-Chromanol CAS No. : 950-99-2 Biological Activity：2,2,5,7,8-Pentamethyl-6-Chromanol (PMC) is the anti-oxidant moiety of vitamin E (α-tocopherol). 2,2,5,7,8-Pentamethyl-6-Chromanol has potent androgen receptor (AR) signaling modulation and anti-cancer activity against prostate cancer cell lines. Research Area：Cancer Targets：Androgen Receptor Related Screening Libraries:Natural Product-like Compound Library;Bioactive Compound Library Plus;Anti-Cancer […]

For research use only. We do not sell to patients. Zuclomiphene citrate CAS No. : 7619-53-6 Biological Activity：Zuclomiphene citrate is a cis isomer of Clomiphene citrate. Zuclomiphene citrate has an antiestrogenic effect and can inhibit the secretion of luteinizing hormone (LH) more than the trans isomer. Zuclomiphene citrate is also an orally active hypocholesterolemic agent[2][3][4]. […]

For research use only. We do not sell to patients. Usmarapride CAS No. : 1428862-33-2 Biological Activity：Usmarapride (SUVN-D4010) is a potent, selective, orally active and brain penetrant 5-HT4 receptor partial agonist (EC50=44 nM). Usmarapride (SUVN-D4010) can be used for the research of cognitive deficits associated with Alzheimer’s disease. Research Area：Neurological Disease Targets：5-HT Receptor Related Screening […]

For research use only. We do not sell to patients. TAK-071 CAS No. : 1820812-16-5 Biological Activity：TAK-071 is a novel, potent and highly selective muscarinic acetylcholine receptor 1 (M1R) positive allosteric modulator. EC50 of TAK-071 M1R agonist activities is 520 nM. Research Area：Neurological Disease Targets：mAChR Related Screening Libraries:Covalent Screening Library Plus;Drug Repurposing Compound Library Plus;Clinical […]

For research use only. We do not sell to patients. Ospemifene D4 Biological Activity：Ospemifene D4 (FC-1271a D4) is a deuterium labeled Ospemifene. Ospemifene is a selective and orally active estrogen receptor modulator for the prevention of osteoporosis with IC50 values of 827 nM and 1633 nM for estrogen receptor α (ERα) and ERβ, respectively. Ospemifene […]

For research use only. We do not sell to patients. TCMDC-136230 Biological Activity：TCMDC-136230 is a novel disruptor of the malaria parasite calcium dynamics but minimally inhibits heme crystallization. Research Area：Infection Targets：Parasite Related Small Molecules:(+)-Isopulegol;SR9186;Antileishmanial agent-2;Azlocillin sodium salt;SQ109;Trypanothione synthetase-IN-3;Pyrantel;α-Terpinene;Dehydrocorydaline;Niclosamide monohydrate;Febrifugine dihydrochloride;Antimalarial agent 15;Cycloguanil hydrochloride;Anti-infective agent 6;Morantel tartrate;Sulfiram;UCB7362;Retro-2;PfDHODH-IN-2;ML251 Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural […]

For research use only. We do not sell to patients. IL-17 modulator 4 sulfate CAS No. : 2446806-90-0 Biological Activity：IL-17 modulator 4 sulfate is a prodrug of IL-17 modulator 1 (HY-141535). IL-17 modulator 1 is an orally active, highly efficacious IL-17 modulator. Research Area：Inflammation/Immunology Targets：Interleukin Related Related Small Molecules:AX-024;Ginsenoside F3;Perakizumab;PNRI-299;CTX-471;Ac-YVAD-CHO;Deucravacitinib;Mulberroside A;NFAT Transcription Factor Regulator-1;IL-17A antagonist […]