Tag: Modulator

For research use only. We do not sell to patients. NGP555 CAS No. : 1304630-27-0 Biological Activity：NGP555 is a γ-secretase modulator. Research Area：Neurological Disease Targets：γ-secretase Related Screening Libraries:Clinical Compound Library Plus; Bioactive Compound Library Plus;Neuronal Signaling Compound Library;Stem Cell Signaling Compound Library;Clinical Compound Library;CNS-Penetrant Compound Library;Anti-Aging Compound Library; Related Small Molecules:γ-Secretase modulator 4;ELN318463;Crenigacestat;Aβ42-IN-1 free base;Fosciclopirox;JNJ-40418677;gamma-secretase […]

For research use only. We do not sell to patients. L-838417 CAS No. : 286456-42-6 Biological Activity：L-838417 is a selective partial agonist at the α2, α3 and α5 subtypes of the GABAA receptor and an antagonist at the α1, with binding Ki values of 0.79 nM, 0.67 nM, 1.67 nM, 267 nM, 2.25 nM and […]

For research use only. We do not sell to patients. IMD-catechol Biological Activity：IMD-catechol is a novel imidazoquinolinone-NF-κB immunomodulator dimer that improves efficacy in a CT26 mouse colon carcinoma tumor model while eliciting minimal adjuvant toxicity. Research Area：Inflammation/Immunology Targets：NF-κB Related Small Molecules:Akt/NF-κB/JNK-IN-1;Icariside F2;IKKγ NBD Inhibitory Peptide TFA;Mangiferin;Antioxidant agent-5;ALPK1-IN-1;Regaloside A;IMD-ferulic;SN52;5-Aminosalicylic Acid-D3 hydrochloride;Ginsenoside Rg1;Echinulin;Licochalcone D;QNZ;BIZ 114;NF-κΒ activator 1;Berbamine;NF-κΒ […]

For research use only. We do not sell to patients. 18:0-22:6 DG CAS No. : 65886-80-8 Biological Activity：18:0-22:6 DG (1-Stearoyl-2-docosahexaenoyl-sn-glycerol) is a diacylglycerol that can bind to RasGRP and modulate MAP kinases activation. Research Area：Others Targets：p38 MAPK Related Small Molecules:SB-747651A dihydrochloride;Dehydrocorydaline;SKF-86002 dihydrochloride;Pexmetinib;SB 242235;TA-01;Anti-inflammatory agent 7;MW-150;VX-702;R1487 Hydrochloride;MBP MAPK Substrate;Isoliquiritin apioside;Sesamolin;MAPK13-IN-1;PF-05381941;Semapimod tetrahydrochloride;SD-169;Skatole;BMS-582949 hydrochloride;Gypenoside L;Dilmapimod;Pamapimod;Andrograpanin;MKK7-COV-9;AMG-47a;Kaempferol-3-O-glucorhamnoside;SB 202190 hydrochloride Trending […]

For research use only. We do not sell to patients. Mutabilol Biological Activity：Mutabilol (compound 1) is a potent p-glycoprotein (P-gp) regulator. Mutabilol is a nature product could be isolated from Plectranthus mutabilis leaves. Mutabilol increases the P-gp expression in NCI-H460/R cells. Research Area：Cancer Targets：P-glycoprotein Related Small Molecules:Biricodar;P-gp inhibitor 4;Sinapine thiocyanate;Dofequidar fumarate;Elacridar;Coniferyl ferulate;Anticancer agent 50;Valspodar;P-gp inhibitor […]

For research use only. We do not sell to patients. NCGC 607 CAS No. : 1462267-07-7 Biological Activity：NCGC607 is a noninhibitory chaperone of glucocerebrosidase (Gcase). Research Area：Cardiovascular Disease Targets：Glucosidase Related Screening Libraries:Bioactive Compound Library Plus;Metabolism/Protease Compound Library;Anti-Cardiovascular Disease Compound Library;Anti-Parkinson’s Disease Compound Library;Neurodegenerative Disease-related Compound Library;Glucose Metabolism Compound Library; Related Small Molecules:α-Glucosidase-IN-20;Ganoderic acid Y;Glucocerebrosidase-IN-1;α-Glucosidase-IN-21;α-Glucosidase-IN-17;Bisabolone oxide […]

For research use only. We do not sell to patients. MS4322 CAS No. : 2375432-47-4 Biological Activity：MS4322 (YS43-22) is a first-in-class PRMT5 degrader and a valuable chemical tool (PROTAC) for exploring the PRMT5 functions in health and disease. Research Area：Cancer Targets：PROTACs Related Screening Libraries:Bioactive Compound Library Plus; Related Small Molecules:PROTAC Sirt2 Degrader-1;DB0614;PROTAC VEGFR-2 degrader-2;dTAGV-1-NEG;CCT367766 formic;HDAC6 […]

For research use only. We do not sell to patients. Betahistine-d3 dihydrochloride CAS No. : 244094-72-2 Biological Activity：Betahistine-d3 dihydrochloride is the deuterium labeled Betahistine dihydrochloride. Betahistine dihydrochloride is an orally active histamine H1 receptor agonist and a H3 receptor antagonist. Betahistine dihydrochloride is used for the study of rheumatoid arthritis (RA)[3]. Research Area：Endocrinology|Inflammation/Immunology|Neurological Disease Targets：Histamine […]

For research use only. We do not sell to patients. cis-11-Methyl-2-dodecenoic acid CAS No. : 677354-23-3 Biological Activity：cis-11-Methyl-2-dodecenoic acid is a quorum sensing (QS) signal that acts as a diffusion signaling factor (DSF) in extracellular microbial and fungal communication systems. DSF is involved in the regulation of virulence and biofilm formation of a variety of […]

For research use only. We do not sell to patients. PK9327 CAS No. : 2413987-20-7 Biological Activity：PK9327 is a small-molecule stabilizer targeting cavity-creating p53 cancer mutations. Research Area：Cancer Targets：MDM-2/p53 Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;Anti-Cancer Compound Library;Autophagy Compound Library;Anti-Aging Compound Library;Ferroptosis Compound Library;Pyroptosis Compound Library;Glutamine Metabolism Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Blood Cancer Compound […]