Tag: Modulator

For research use only. We do not sell to patients. Eptazocine CAS No. : 72522-13-5 Biological Activity：Eptazocine (Sedapain) is a κ-opioid receptor agonist and μ-opioid receptor antagonist. Eptazocine has the effect of relieving pain. Research Area：Neurological Disease Targets：Opioid Receptor Related Small Molecules:ORL1 antagonist 1;Loperamide-d6 N-Oxide;Deltorphin 2 TFA;Nalfurafine;β-Lipotropin (60-65);GSK1521498 free base;Trimebutine-d5 fumarate;Dynorphin B (1-13) (TFA);Dermorphin Analog;β-Endorphin […]

For research use only. We do not sell to patients. 5-HT1A modulator 2 hydrochloride CAS No. : 3880-76-0 Biological Activity：5-HT1A modulator 2 hydrochloride, a derivative of 8-OH-DPAT (HY-112061), is a modulator of 5-HT1A with a Ki of 53 nM for 5-HT1A binding. Research Area：Neurological Disease Targets：5-HT Receptor Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G Protein Compound […]

For research use only. We do not sell to patients. TCMDC-125457 CAS No. : 872113-12-7 Biological Activity：TCMDC-125457 is potent in inducing calcium redistribution but minimally inhibits heme crystallization. TCMDC-125457 demonstrated high efficacy when pulsed in a single-dose combination with artesunate against tightly synchronized artemisinin-resistant ring-stage parasites. Research Area：Infection Targets：Parasite Related Small Molecules:(+)-Isopulegol;SR9186;Antileishmanial agent-2;Azlocillin sodium salt;SQ109;Trypanothione […]

For research use only. We do not sell to patients. Adrenocorticotropic hormone CAS No. : 9002-60-2 Biological Activity：Adrenocorticotropic hormone (ACTH) is a polypeptide tropic hormone produced by the anterior pituitary gland. Adrenocorticotropic hormone regulates cortisol and androgen production[2]. Research Area：Endocrinology Targets：Androgen Receptor Related Small Molecules:VPC-14449;AC-262536;GTx-007;Linuron-d6;MI-136;VPC-13789;RD162;ARD-2585;PF-998425;GSK-2881078;PROTAC AR Degrader-4;RU 58841;Triptophenolide;ARD-61;Dehydroisoandrosterone 3-acetate;Topilutamide;CSRM617 hydrochloride;ARD-2128;A4B17;MK-0773;LH-RH II (chicken) Trending products：Recombinant Proteins  […]

For research use only. We do not sell to patients. AZ 12216052 CAS No. : 1290628-31-7 Biological Activity：AZ 12216052 is a mGluR8 positive allosteric modulator, and helps mGluR8 modulate signaling inputing to retinal ganglion cells. AZ 12216052 exhibits antianxiety effect[2][3][4]. Research Area：Neurological Disease Targets：mGluR Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Neuronal Signaling Compound […]

For research use only. We do not sell to patients. VU0483605 CAS No. : 1623101-11-0 Biological Activity：VU0483605 is a potent and brain-penetrated mGlu1 receptor positive allosteric modulator (PAM). VU0483605 shows excellent mGlu1 PAM activity at both human and rat, with EC50 values of 390 and 356 nM, respectively. Research Area：Others Targets：mGluR Related Screening Libraries:Bioactive Compound […]

For research use only. We do not sell to patients. RORγt modulator 3 CAS No. : 2230877-38-8 Biological Activity：RORγt modulator 3 (Compound 23) is a modulator of retinoid-related orphan receptor γt (RORγt). RORγt modulator 3 can be used for the research of RORyt mediated diseases such as, e.g., pain, inflammation, COPD, asthma, rheumatoid arthritis, colitis, […]

For research use only. We do not sell to patients. (E/Z)-4-Hydroxytamoxifen CAS No. : 68392-35-8 Biological Activity：(E/Z)-4-Hydroxytamoxifen (Afimoxifene) is a racemic compound of (Z)-4-Hydroxytamoxifen and (E)-4-Hydroxytamoxifen isomers. (E/Z)-4-Hydroxytamoxifen is an estrogen receptor modulator. Research Area：Cancer Targets：Estrogen Receptor/ERR|Endogenous Metabolite Related Screening Libraries:Natural Product-like Compound Library;Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Metabolism/Protease Compound […]

For research use only. We do not sell to patients. CXCR4 modulator-1 CAS No. : 1381178-26-2 Biological Activity：CXCR4 modulator-1 (compound ZINC72372983) is a potent CXCR4 modulator with an EC50 value of 100 nM. CXCR4 modulator-1 can be used for researching anti-inflammatory, anticancer and anti-HIV. Research Area：Cancer|Infection|Inflammation/Immunology Targets：CXCR Related Small Molecules:Nicotinamide N-oxide;FC131;CXCR4 antagonist 2;AMG 487 (S-enantiomer);CXCR4 […]

For research use only. We do not sell to patients. α1 adrenoceptor-MO-1 CAS No. : 161905-64-2 Biological Activity：α1 adrenoceptor-MO-1, an S enantiomer, has affinity at alpha 1 adrenergic receptor, shows alphalytic activity, and possesses analgesic action; more active than R enantiomer. Research Area：Neurological Disease|Endocrinology Targets：Adrenergic Receptor Related Small Molecules:Todralazine;ARC 239 dihydrochloride;Yohimbine;Glaucine;Salbutamol;BI-167107;Talibegron hydrochloride;Arotinolol;SR59230A;Higenamine hydrochloride;Navafenterol saccharinate;Isoprenaline hydrochloride;Bevantolol;Zilpaterol-d7;Ritanserin;A55453;Povafonidine;β3-AR […]